نتایج جستجو برای: copper sulfateseizurepentylenetetrazole valproic acid

تعداد نتایج: 821568  

Journal: :مجله علوم اعصاب شفای خاتم 0
rashin khalaj department of biology, faculty of basic sciences, university of mazandaran, babolsar, iran akbar hajizadeh moghaddam department of biology, faculty of basic sciences, university of mazandaran, babolsar, iran mahbobeh zare faculty of herbs, amol university of special modern technologies, amol, iran sedigheh khanjani jelodar faculty of biology, shahid beheshti university, tehran, iran

introduction: autism spectrum disorders (asd) are a heterogeneous group of neurodevelopmental disorders that are defined with a wide range of behavioral impairments including social and communication deficits. apart from these core symptoms, a significant number of asd individuals display higher levels of anxiety. the present study is designed to understand the antioxidant efficacy of hesperetin...

2015
Eui Kyu Chie Jin Hee Shin Jin Ho Kim Hak Jae Kim In Ah Kim Il Han Kim

PURPOSE This study was conducted in order to validate the radiosensitization effect of valproic acid, a biologically available histone deacetylase inhibitor, for fractionated radiation. MATERIALS AND METHODS Radiosensitization effect of valproic acid was tested for the A549 cell line and U87MG cell line in vitro. Fractionated irradiation of 12 Gy in four fractions was administered on D2-5 wit...

2014
Jennifer D. Twilla Andrew S. Pierce

Valproic acid-induced hyperammonemic encephalopathy is a rare yet serious adverse drug reaction. Medication interactions such a valproic acid and topiramate can precipitate an event. We present the case of a 52-year-old female that presented with acute mental status change and hypersomnolence due to hyperammonemia caused by a valproic acid derivative. The patient improved after withdrawal of th...

Objective(s): Valproic and arundic acids are astrocytes-modulating agents with potential effects in the treatment of Alzheimer’s disease (AD). S100B is an astrocytic cytokine with a possible role in the pathogenesis of AD. In this study, we aimed to assess the glioprotective effects of valproic and arundic acids against amyloid-β-peptide (Aβ)-induced glial death and co...

Journal: :Reactions Weekly 2021

Journal: :Journal of psychiatry & neuroscience : JPN 2004
Giuseppe Tringali Jean Michel Aubry Katiuscia Moscianese Claudia Zamori Mauro Vairano Paolo Preziosi Pierluigi Navarra Giacomo Pozzoli

OBJECTIVE Corticotropin-releasing factor (CRF), the major adrenocorticotropic hormone (ACTH) secretagogue, acts within the brain to integrate the stress responses of the central nervous, endocrine and immune systems. The involvement of this peptide in the origin and pathophysiology of various endocrine, neurologic, inflammatory and psychiatric diseases, particularly affective disorders, has als...

2010
A. Wittenburg Daniel L. Gustafson Douglas H. Thamm

wnloade pose: Histone deacetylase inhibitors (HDACi) are targeted anticancer agents with a well-documenility to act synergistically with cytotoxic agents. We recently showed that the HDACi valproic acid izes osteosarcoma cells to doxorubicin in vitro and in vivo. As there are no published reports on the l utility of HDACi in dogs with spontaneous cancers, we sought to determine a safe and biolo...

Journal: :Pediatric Research 1987

2017
KARTHIKA ASHOK KUMAR CHANSHI CHANDRAN REMYA REGHU

Valproic acid is commonly used in the treatment of both focal and generalized epilepsies and is often tolerated well. Valproic acid is usually tolerated well, but serious complications, including hepatotoxicity and hyperammonemic encephalopathy, may occur. Here, we report a case of valproic acidinduced hyperammonemic encephalopathy on concomitant use with lacosamide.

2012
Barbara Kaczorowska-Hac Agnieszka Matheisel Lucyna Maciejka-Kapuscinska Jakub Wisniewski Anna Alska Elzbieta Adamkiewicz-Drozynska Anna Balcerska Iwona Reszczynska

INTRODUCTION Valproic acid is a commonly used anti-epileptic drug. Hematological toxicities are among the occasionally observed adverse effects of this medication. CASE PRESENTATION We present the case of a 13-year-old Caucasian boy who demonstrated mild anemia 12 months after the introduction of valproic acid therapy. A bone marrow biopsy revealed maturation arrest of proerythroblasts. CON...

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