The management of stroke and transient ischaemic attacks (TIAs) has changed greatly in the last two decades. The importance of good blood pressure control is the hallmark of stroke prevention. Large multicentre trials have proven beyond doubt the value of aspirin in TIAs, warfarin in patients with atrial fibrillation and embolic cerebrovascular symptoms, and carotid endarterectomy in patients w...

The regional cerebral metabolism-to-perfusion imbalance has been studied in the three main categories of cerebrovascular disorders in a chronic phase of the disease, using the non-invasive oxygen-15 inhalation technique. In patients presenting with a history of transient ischaemic attacks, regional defects in cerebral perfusion were greater than for the corresponding oxygen uptakes. Areas of re...

Two hundred fifteen consecutive patients with cerebrovascular events were evaluated prospectively for the incidence and characteristics of headache. Of 163 patients able to communicate, headache occurred in 29% with bland infarcts, 57% with parenchymal hemorrhage, 36% with transient ischemic attacks and 17% with lacunar infarcts. Patients with a history of recurrent throbbing headache were sign...

BACKGROUND AND PURPOSE Retrospective studies have found a close correlation between an impaired cerebrovascular reserve capacity and the incidence of hemodynamic stroke. The present study evaluates this relation prospectively. METHODS We measured the CO2 reactivity in 85 patients with internal carotid artery occlusions by transcranial Doppler sonography (Doppler CO2 test). All patients were p...

Reassessment of Anticoagulant Therapy in Various Types of Occlusive Cerebrovascular Disease • Precise use of categorical terms and definitions is mandatory in discussing the use of anticoagulants in treating occlusive cerebrovascular disease. The components of the temporal profile of the disease are described. Six reports have appeared which describe the results of anticagulant therapy in trans...

no abstract

Prof. Dr. Carlo Loeb, Istituto di Clinica Neurologica dell’Università di Genova, I-16132 Genova (Italy) Over the last few years various definitions have been coined to indicate ischemic attacks receding later than 24 h from their onset: strokes with full recovery (6th International Salzburg Conference, 1972), reversible ischemic neurological deficit (Handbook of Clinical Neurology, 1972; Ad hoc...

OBJECTIVES In 2011, the California Right Care Initiative implemented a countywide physician organization learning collaborative called University of Best Practices (UBP) in San Diego County for major healthcare systems and physician organizations to share best practices in managing cardiovascular and cerebrovascular risk factors. Our objective was to examine whether UBP was associated with fewe...

OBJECTIVES The goal of this study was to investigate whether complex aortic atherosclerosis is associated with increased risk of vascular events in a non-selected population. BACKGROUND In selected high-risk patients, aortic atherosclerosis is associated with increased risk of vascular events. METHODS We describe the relationship between simple versus complex (>4-mm thick or mobile debris) ...