1 Carbimazole was administered to nine hyperthyroid patients, and blood samples were taken at various time intervals for analysis of carbimazole, and its metabolite methimazole.2 A technique was developed for the measurement of methimazole in serum using a High-Pressure Liquid Chromatograph, which could detect nanogram quantities of this metabolite.3 After a single oral dose, the patients' bloo...

This study provides for the first time clear evidence that block and replace (BR) strategy (combination of carbimazole plus levothyroxine) is not superior to dose titration (DT) treatment paediatric Graves’ disease.

A 64-year-old man presented to the dermatology outpatient clinic with a 4-month history of pruritic papules. He had significant medical thyrotoxicosis, which was diagnosed 1 year prior and well controlled on carbimazole. no dyslipidaemia or underlying malignancy. The cutaneous eruption first started his abdomen, over

An experiment was conducted to investigate the effect of thyroid gland activity modulation (Hyper or hypothyroidism) on energy utilization in broiler chickens. Two hundred and forty one-day-old Cobb broiler chicks were distributed into three dietary metabolizable energy (ME) treatment groups (80 chicks each). The control group (E0) was fed basal diet (3150 kcal/kg diet), the second group (E1) w...