background and objectives: complement proteins are some of the most important plasma proteins of the innate immune system. impaired immune function is reported in subjects who are iron deficient, and there are documents that these patients are prone to infection. this study was conducted to show whether serum c3 and c4 complement change in adult nonpregnant female with iron deficient anemia or ...

It is shown that Darwiche and Pearl's postulates imply an interesting property, not noticed by the authors. In [?], Darwiche and Pearl propose postulates for iterated revisions, noted (R*1) to (R*6) and (C1) to (C4). In particular, the postulate (C3) reads: (C3) If Ψ • α |= µ, then (Ψ • µ) • α |= µ. It will be shown that, in the presence (R*1) to (R*6), (C1) and (C3) imply: (* *) If Ψ • α |= µ,...

AIM: To evaluate the potential of two trabecular meshwork (TM)-specific promoters, Chitinase 3-like 1 (Ch3L1) and matrix gla protein (MGP), for improving specificity safety in glaucoma gene therapy based on self-complementary AAV2 (scAAV2) vector technologies. METHODS: An scAAV2 with C3 transferase (C3) as reporter (scAAV2-C3) was selected. The scAAV2-C3 vectors were driven by Ch3L1 (scAAV2-Ch3...

More than 90% of patients with type III hyperlipoproteinemia are homozygous carriers of the apolipoprotein (apo) E*2 allele. The great majority of these apoE2(Arg158-->Cys) homozygotes in the general population, however, are normolipidemic. Apparently, expression of the hyperlipidemic state requires additional genetic and/or environmental factors, suggesting a multifactorial etiology. To elucid...

in this survey, opsonization activity of sera in 110 patients with meningitis, sepsis and recurrent infection 12 patients after healing and 50 normal adults has been studied. opsonization activity was measured by an assay depending on electronic particle counting to measure yeast uptake (alternative pathway activator) which was modified in our laboratory. three classes of immunoglobulins (lgg, ...

Slow wave oscillations in the electroencephalogram (EEG) during sleep may reflect both sleep need and intensity, which are implied in homeostatic regulation. Adenosine is strongly implicated in sleep homeostasis, and a single nucleotide polymorphism in the adenosine deaminase gene (ADA G22A) has been associated with deeper and more efficient sleep. The present study verified the association bet...

In this survey, opsonization activity of sera in 110 patients with meningitis, sepsis and recurrent infection 12 patients after healing and 50 normal adults has been studied. Opsonization activity was measured by an assay depending on electronic particle counting to measure yeast uptake (alternative pathway activator) which was modified in our laboratory. Three classes of immunoglobulins (...