نتایج جستجو برای: bioavailability encapsulation liposomes phytosomes plant extract
تعداد نتایج: 588237 فیلتر نتایج به سال:
A Narrative Review of the Potential Roles of Lipid-Based Vesicles (Vesiculosomes) in Burn Management
Burn injuries can have a lasting effect on people’s quality of life, as they negatively impact their physical and mental health. Then, are likely to suffer psychological problems result. A serious problem is that deep burns more challenging treat due slow healing rate susceptibility microbial infection. Conventional topical medications used for burn treatment sometimes ineffective because canno...
BACKGROUND AND AIMS Although the beneficial effects of statins on stroke have been widely demonstrated both in experimental studies and in clinical trials, the aim of this study is to prepare and characterize a new liposomal delivery system that encapsulates simvastatin to improve its delivery into the brain. MATERIALS AND METHODS In order to select the optimal liposome lipid composition with...
Photoaging causes the dermis and collagen fibers to decrease which results in skin aging. Genus Bacillus has SOD activity as an anti-photoaging agent that can neutralize ROS (Reactive Oxygen Species) due exposure UV-A rays. This study aimed examine of crude extract encapsulation characteristics liposomes from B. altitudinis. The began with isolation enzyme, determination total protein content e...
Chrysin (CHR), a flavone found in multiple vegetables, fruits and mushrooms has been explored so far as neurotropic, anti-inflammatory anti-cancer biomolecule. Despite the stated therapeutic potential, low solubility bioavailability limit its benefit. To circumvent these drawbacks, development of chrysin liposomes (CLPs) is reported present investigation. The CLPs were developed by electrostati...
Luteolin is a falconoid compound that is present in various types of plants and possesses remarkable potential as a chemopreventive agent. However, the poor aqueous solubility of luteolin limits its clinical application. In the present study, an approach towards chemoprevention was explored using liposomes to deliver luteolin, and the antitumor efficacy was investigated in colorectal carcinoma....
Doxorubicin is a potent antineoplastic agent with activity against numerous human cancers. Encapsulation of doxorubicin inside a liposome alters bioavailability, biodistribution and thus its biological activity significantly. The physical properties of the liposome (size, lipid components and lipid dose) play a major role in determining drug retention and pharmacokinetics. The therapeutic benef...
Resistance of microorganisms to antibiotics has increased. The use of natural components with antimicrobial properties can be of great significance to reduce this problem. The presented work is focused on the study of the effect of encapsulation of selected plant and animal antimicrobial substances (herbs, spices, lysozyme and nisin) on their activity and stability. Antimicrobial components wer...
Drug development is a key point in the research of new therapeutic treatments for increasing maximum drug loading and prolonged drug effect. Encapsulation of drugs into multivesicular liposomes (DepoFoam) is a nanotechnology that allow deliver of the active constituent at a sufficient concentration during the entire treatment period. This guarantees the reduction of drug administration frequenc...
Drug development is a key point in the research of new therapeutic treatments for increasing maximum drug loading and prolonged drug effect. Encapsulation of drugs into multivesicular liposomes (DepoFoam) is a nanotechnology that allow deliver of the active constituent at a sufficient concentration during the entire treatment period. This guarantees the reduction of drug administration frequenc...
Bioactive compounds possess a variety of potentially beneficial bioactivities. However, the application these ingredients in food, supplement and pharmaceutical industries is often challenged due to their poor solubility, low chemical stability, unsustainable bioavailability. Carvacrol, for example, can represent wide range bioactive that are susceptible processing, transportation storage condi...
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