نتایج جستجو برای: b22
تعداد نتایج: 150 فیلتر نتایج به سال:
Cytotoxic T lymphocytes (CTL) can recognize antigenic peptides bound in a groove formed by the od and ol2 domains of the heterodimeric major histocompatibility complex class I molecule. Proper assembly, transport, and stability of functional class I molecules is thought to require 32 microglobulin (32m), the light chain of the class I heterodimer. We show here that the requirement for 32m is no...
Recent developments in econometrics and economic theory attest the growing evidence of strong uncertainty. The paper argues that these developments both question seriously the methodological foundations of the mainstream macroeconomics and support Keynes’s powerful concepts and theory. It emphasizes how replacing ‘risk’ with strong uncertainty suffices to transform the standard four-macro-marke...
Some novel fused heterocyclic compounds of 2,5-disubstituted-benzoxazole derivatives, which were previously synthesized by our group, were investigated for their mutagenic properties on Salmonella typhimurium TA 98 and TA 100 strains, cytotoxic activity in L929 and HeLa cell lines by Sulforhodamine B (SRB) cytotoxicity test, and genotoxic potentials in the comet assay. By using Ames/Salmonella ...
Insulin is a key hormone of human metabolism with major therapeutic importance for both types of diabetes. New insulin analogues with more physiological profiles and better glycemic control are needed, especially analogues that preferentially bind to the metabolic B-isoform of insulin receptor (IR-B). Here, we aimed to stabilize and modulate the receptor-compatible conformation of insulin by co...
In the cofermentation of glycerol with a sugar by Lactobacillus brevis and Lactobacillus buchneri, a 1,3-propanediol:NAD+ oxidoreductase provides an additional method of NADH disposal. The enzyme has been purified from both L. brevis B22 and L. buchneri B190 and found to have properties very similar to those reported for the enzyme from Klebsiella pneumoniae. The enzymes required Mn2+ and are p...
Shoham, proposed, a uniform approach to systems for nonmonotonic reasoning, which consists in considering standard logics augmented with a preference relation on the interpretations. Circumscription can easily -seen. to be a special case of this preference logic framework, but capturing default logic turned out to-be, more difficult, and is even thought to be impossible by some researchers of n...
A protocol has been developed to distinguish between wild-type, heterozygous and homozygous oim mutant mice. Oim mice (The Jackson Laboratory, Bar Harbor, ME, USA) have a singlebase deletion in their proα2(I) collagen gene (cola-2 gene). This mutation changes the reading frame at the 3′ end of the mRNA causing synthesis of an altered C-propeptide that ultimately inhibits association of these mo...
We study the minimal normal completion problem: given A ∈ Cn×n, how do we find an (n+q)×(n+q) normal matrix Aext := ( A A12 A21 A22 ) of smallest possible size? We will show that this smallest number q of rows and columns we need to add, called the normal defect of A, satisfies nd(A) ≥ max{i−(AA∗ −A∗A), i+(AA∗ −A∗A)}, where i±(M) denotes the number of positive and negative eigenvalues of the He...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید