نتایج جستجو برای: arsb gene

تعداد نتایج: 1141400  

2015
Yiren Yang Shiyang Wu Ross McCausland Lilley Ren Zhang

Transporter-facilitated arsenite extrusion is the major pathway of arsenic resistance within bacteria. So far only two types of membrane-bound transporter proteins, ArsB and ArsY (ACR3), have been well studied, although the arsenic transporters in bacteria display considerable diversity. Utilizing accumulated genome sequence data, we searched arsenic resistance (ars) operons in about 2,500 bact...

2013
Sandra Jester Julia Larsson Erik A Eklund Domniki Papadopoulou Jan-Eric Månsson Albert N Békássy Dominik Turkiewicz Jacek Toporski Ingrid Øra

BACKGROUND Mucopolysaccharidosis VI (MPS VI) is an autosomal recessive progressive multiorgan disorder due to mutation in the gene encoding the enzyme Arylsulfatase B (ARSB). Dysfunctional ARSB causes lysosomal accumulation of glycosaminoglycans (GAG). Currently, enzyme replacement therapy (ERT) is preferred to hematopoietic stem cell transplantation (SCT) due to the treatment-related risks of ...

2013
Suriana Sabri Jennifer A Steen Mareike Bongers Lars K Nielsen Claudia E Vickers

BACKGROUND Metabolic engineering projects often require integration of multiple genes in order to control the desired phenotype. However, this often requires iterative rounds of engineering because many current insertion approaches are limited by the size of the DNA that can be transferred onto the chromosome. Consequently, construction of highly engineered strains is very time-consuming. A lac...

2013
Yiren Yang Xuefei Yu Ren Zhang

We report the 4.97-Mb draft genome sequence of a highly efficient arsenate-resistant bacterium, Ochrobactrum sp. strain CDB2. It contains a novel arsenic resistance (ars) operon (arsR-arsC1-ACR3-arsC2-arsH-mfs) and two non-operon-associated ars genes, arsC3 and arsB. The genome information will aid in the understanding of the arsenic resistance mechanism of this and other bacterial species.

Journal: :Applied and environmental microbiology 2003
Chad W Saltikov Ana Cifuentes Kasthuri Venkateswaran Dianne K Newman

Arsenate [As(V); HAsO(4)(2-)] respiration by bacteria is poorly understood at the molecular level largely due to a paucity of genetically tractable organisms with this metabolic capability. We report here the isolation of a new As(V)-respiring strain (ANA-3) that is phylogenetically related to members of the genus Shewanella and that also provides a useful model system with which to explore the...

2018
Leonardo N. Andrade Thiago E. S. Siqueira Roberto Martinez Ana Lucia C. Darini

Bacterial resistance to antibiotics is concern in healthcare-associated infections. On the other hand, bacterial tolerance to other antimicrobials, like heavy metals, has been neglected and underestimated in hospital pathogens. Silver has long been used as an antimicrobial agent and it seems to be an important indicator of heavy metal tolerance. To explore this perspective, we searched for the ...

Journal: :Molecular Genetics and Metabolism Reports 2015

Journal: :Dalton transactions 2015
Julian Brünig Emanuel Hupf Enno Lork Stefan Mebs Jens Beckmann

Oxidative chlorination of ArSbCl2 (1) with SO2Cl2 provided ArSbCl4 (2), the base hydrolysis of which gave rise to the arylstibonic acid (ArSb)4O6(OH)4 (3) having an adamantane type structure. The intramolecularly coordinating substituent Ar = 6-diphenylphosphinoacenaphth-5-yl- modulates the Lewis acidity of 1-3 and prevents extensive aggregation.

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