Active pharmaceutical ingredients (APIs) are the molecular entities that exert the therapeutic effects of medicines. This article provides an overview of the major APIs that are entered into antiretroviral therapy (ART), outlines how APIs are manufactured, and examines the regulatory and cost frameworks of manufacturing ART APIs used in low- and middle-income countries (LMICs). Almost all APIs ...

API users experience significant difficulties when learning how to use APIs, but little is known about the strategies used to overcome these difficulties, the motivation for each strategy, or the trade-offs between the strategies. To better understand the information seeking strategies of API users, we conducted a study in which 20 participants were asked to complete programming tasks using unf...

A fundamental characteristic of Web APIs is the fact that, de facto, providers hardly follow any standard practices while implementing, publishing, and documenting their APIs. As a consequence, the discovery and use of these services by third parties is significantly hampered. In order to achieve further automation while exploiting Web APIs we present an approach for automatically extracting re...

Web APIs are increasingly becoming an integral part of web or mobile applications. As a consequence, performance characteristics and availability of the APIs used directly impact the user experience of end users. Still, quality of web APIs is largely ignored and simply assumed to be su ciently good and stable. Especially considering geo-mobility of today’s client devices, this can lead to negat...

Modelling and understanding various contexts of users is important to enable personalised selection of Web APIs in directories such as Programmable Web. Currently, relationships between users and Web APIs are not clearly understood and utilized by existing selection approaches. In this paper, we present a semantic model of a Web API directory graph that captures relationships such as Web APIs, ...

Globalization has provided opportunities for parasites/pathogens to cross geographic boundaries and expand to new hosts. Recent studies showed that Nosema ceranae, originally considered a microsporidian parasite of Eastern honey bees, Apis cerana, is a disease agent of nosemosis in European honey bees, Apis mellifera, along with the resident species, Nosema apis. Further studies indicated that ...

Antibiotics, particularly oxytetracycline, have been discussed as a possible predisposing condition in the appearance of chalkbrood in the honeybee (Apis mellifera L.). Nevertheless, the scientific data to support this belief have been insufficient. We have developed a method to study the effects of this antibiotic as a predisposing factor under different circumstances. We conclude that oxytetr...

b a ckground: the varroa destructor mite is considered as a major pest of honey bees apis mellifera . the rapid spread of varroa mites among bee colonies may be due to several factors, including drifting of infested bees, movement of bee swarms, and robbing of weakened colonies. disease spread and predisposing the infested bees to other diseases lead to high economic losses in beekeeping indust...

A number of approaches combine the principles and technologies of Linked Data and RESTful services. Services and APIs are thus enriched by, and contribute to, the Web of Data. These resource-centric approaches, referred to as Linked APIs, focus on flexibility and the integration capabilities of Linked Data. We use our experience in teaching students on how to use Linked APIs to identify the exi...

Object-oriented Application Programing Interfaces (APIs) support software reuse by providing pre-implemented functionalities. Due to the huge number of included classes, reusing and understanding large APIs is a complex task. Otherwise, software components are admitted to be more reusable and understandable entities than object-oriented ones. Thus, in this paper, we propose an approach for reen...