Pilocytic astrocytoma (PA) is a circumscribed neoplasia considered as a grade I astrocytoma by the World Health Organization. Its most common location is the cerebellum and it develops during the first two decades of the life. Prognosis is mostly excellent if gross-total resection can be achieved, with 10-year survival rates of up to 80%. Anaplastic or malignant transformation (MT) can rarely o...

Astrocytoma is one of the most common types of brain tumor, which is histologically and clinically classified into four grades (I-IV): I (pilocytic astrocytoma), II (diffuse astrocytoma), III (anaplastic astrocytoma), and IV (glioblastoma multiforme). A higher grade astrocytoma represents a worse prognosis and is more aggressive. In this study, we compared the differential proteome profile of a...

background & objectives: the accurate assessment of the diseased tissue is fundamental to the diagnosis and management of disorders of the central nervous system (cns). the ‛squash’ or ‛crush’ technique has been universally employed in the intraoperative diagnosis of cns tumors. the aim of our study was to evaluate the accuracy of squash preparation in diagnosing cns tumors by comparing wit...

Pilocytic astrocytoma (PA) is the benign variant of astrocytic tumours. Pilocytic(Greek word Pilos=hair) refers to frequent presence of cells with bipolar hairlike processes. Pilocytic tumours are juvenile astrocytomas commonly presenting during first two decades of life with a lowered occurrence in adults. Cerebellum is the favoured site. Spinal cord is the rare site of presentation. We report...