The relation between estrogen receptors (ER) and argyrophilic nucleolar organizer regions (AgNORs) in situ within human breast cancer cells was analyzed. For AgNOR measurements in 49 invasive breast carcinomas, a new reproducible staining method for dual demonstration of ER and AgNORs was applied. Quantitative AgNOR variables were determined in ER-positive and ER-negative tumor cells by digital...

AIMS To see whether a correlation exists between clinicopathological parameters, argyrophilic nucleolar organiser regions (AgNORs), and nucleolar counts in the nuclei of tumour cells in patients with transitional cell bladder carcinoma. METHODS Paraffin wax embedded sections from a total of 62 cases of primary transitional cell bladder carcinoma were stained with the silver colloid method. Th...

The present study was undertaken to provide more information on the incidence of satellite nucleoli in developmental stages of the megakaryocytic lineage. Satellite nucleoli representing solitary silver stained nucleolus organizer regions (AgNORs) present in nuclei in addition to other nucleolar types were observed in all stages of megakaryocytic development. However, the incidence of satellite...

One of the most recent methods to determine the proliferative activity is silver stained nucleolar organizer region(AgNORs).The purpose of present study is by using mean AgNOR count per nucleus was found to be higher in benign soft tissue tumour as compared to apparently normal soft tissue and found to be statistically significant. An increase AgNOR score in benign, intermediate, malignant soft...

To investigate the histopathological characteristics of inverted papillomas of the urinary bladder, including the possibility of malignant transformation, we studied the indicators of cellular proliferation activity in 7 inverted papillomas of the bladder including two cases of malignant inverted papilloma of the bladder. PCNA expression rates in two cases of malignant inverted papilloma were h...

Para realizacao deste estudo foram selecionados quinze casos de Ceratocisto Odontogenico e submetidos a tecnica histoquimica AgNOR imuno-histoquimica do PCNA. Observou-se que o possui uma media 1,84 AgNORs por nucleo 74,98% das celulas sao positivas ao Uma caracteristica constante foi tanto para quanto PCNA camada suprabasal apresentou medias estatisticamente superiores basal. Conclui-se, porta...

The study sought a correlation between the number of AgNOR granules and the degree of cervical intraepithelial neoplasia (CIN). Thirty-five sections (5 normal, 10 CIN1, 10 CIN2 and 10 CIN3) were subjected to retrospective analysis. The percentage of cells with 1, 2, 3, 4 and more AgNORs was calculated and the number of granules per 100 cells was counted. The number of cells containing single gr...

A silver colloid technique to identify nucleolar organiser region associated protein (AgNOR) was applied to 16 fibrous proliferations of childhood and six low grade fibrosarcomas. The fibrous proliferations comprised five cases of infantile digital fibromatosis, seven of infantile desmoid type fibromatosis, and four of infantile myofibromatosis. The AgNORs were visualised as dots within the nuc...

conclusions the agnor technique can be used to diagnose salivary gland tumors. results the chi-square test showed significant differences between tumor types and the numbers of agnors (p = 0.000) and between tumor types and areas of agnors (p = 0.000). objectives the purpose of this study was to determine the numbers and mean areas of the agnor dots in the 3 most common salivary gland tumors. m...