The phase transfer catalysed nucleophilic displacement of 1,3-bis(bromomethyl)benzene, 2-methoxy-5methyl-1,3-bis(bromomethyl)benzene (2) and 1,4-bis(bromomethyl)benzene with 2-mercaptoethanol gives the respective diols 3, 4 and 12 (80–85%), which undergo intermolecular cyclodehydrochlorination with thiodiglycolyl dichloride and pyridine-2,6-dicarbonyl dichloride?HCl to provide m-phenylene (7–10...

Postoperative radiotherapy (RT) is utilized routinely in the management of anaplastic World Health Organization Grade III gliomas (AG), including anaplastic astrocytoma (AA) and anaplastic oligodendroglioma (AO). However, the optimal role of RT in elderly AG patients remains controversial. We evaluated the effectiveness of RT in elderly AG patients using a national cancer registry. The USA Surv...

T-cell activation in lymph nodes relies on encounters with antigen (Ag)-bearing dendritic cells (DCs) but the number of DCs required to initiate an immune response is unknown. Here we have used a combination of flow cytometry, 2-photon imaging, and computational modeling to quantify the probability of T cell-DC encounters. We calculated that the chance for a T cell residing 24 hours in a murine...

Probabilistic material flow analysis and graph theory were combined to calculate predicted environmental concentrations (PECs) of engineered nanomaterials (ENMs) in Swiss rivers: 543 river sections were used to assess the geographical variability of nano-TiO(2), nano-ZnO and nano-Ag, and flow measurements over a 20-year period at 21 locations served to evaluate temporal variation. A conservativ...

Phialophora verrucosa is a dematiaceous fungus able to cause chromoblastomycosis, phaeohyphomycosis and mycetoma. All these fungal diseases are extremely difficult to treat and often refractory to the current therapeutic approaches. Therefore, there is an urgent necessity to develop new antifungal agents to combat these mycoses. In this context, the aim of the present work was to investigate th...

The study focuses on the effects of Ag (silver) and Ti (titanium) ions textiles by MEVVA (metal vapor vacuum arc) ion implantation. In order to comprehend this, research was executed in three parts. first part, antibacterial efficiencies TiO2 were investigated detail since capabilities are well known. A group polyester- cotton-based medical modified ions, with doses ranging from 5 × 1015 1016 i...

In gold (Au) exploration, the analysis of both bulk leach extractable (BLEG) and acid-extractable Au in <180μm stream sediment fraction are two most common approaches. The Eskişehir- Sivrihisar region Western Türkiye hosts several orogenic type mineral deposits. purpose this study is to delineate geochemical anomalies ore-related elements track their dispersion, which may lead discovery unknown...

As a promising midtemperature thermoelectric material with both higher performance and mechanical property, Tellurium Antimony Germanium Silver (TAGS- x ), written as (GeTe) (AgSbTe 2 ) 1- , especially 0.85 0.15 (TAGS-85), has attracted wide attention. Herein, we innovatively use Nd doping to synergistically decrease the carrier concentration optimal level leading enhanced dimensionless figure ...

The low performance or high cost of commercially available conductive inks limits the advancement of printed electronics. This article studies the explosion of metal wires in aqueous solutions as a simple, low-cost, and environmentally friendly method to prepare metallic nanoparticles consisting of Cu and Cu alloys for use in affordable, highly conductive inks. Addition of 0.2 M ascorbic acid t...