A new protocol for Ru-catalyzed decarboxylative cyclization of mandelic acids with acrylates was established, which allows efficient construction of the phthalide skeleton. Interestingly, this reaction underwent a decarboxylative process, in which only divinylation was observed, and the subsequent cyclization led to the formation of phthalides.

BACKGROUND Ultraviolet (UV)-curing nail polishes based on acrylates or methacrylates are currently also available for non-professional use. The Swedish Medical Products Agency recently prohibited one brand of UV-curing polish, because several consumers reported undesirable effects after using it. OBJECTIVES To investigate whether consumers with undesirable effects after using the UV-curing na...

Cobalt complex/Zn systems effectively catalyze the reductive coupling of activated alkenes with alkynes in the presence of water to give substituted alkenes with very high regio- and stereoselectivity in excellent yields. While the intermolecular reaction of acrylates, acrylonitriles, and vinyl sulfones with alkynes takes place in the presence of CoI2(PPh3)2/Zn, the reaction of enones and enals...

Solid-state emission color change upon mechanical stimuli, known as mechanofluorochromism (MFC), is reported for pyrenyl acrylates. The C-1- and C-4-alkenylated pyrenes ((E)-Ethyl-3-(Pyren-1-yl)acrylate (E)-Ethyl-3-(Pyren-4-yl)acrylate, respectively) exhibited distinct MFC behaviors (hypsochromic bathochromic shifts). introduction of bulky tert-butyl groups in 2,7-position ((E)-Ethyl-3-(2,7-Di-...

A copper-catalyzed conjugate addition of alkylboron compounds (alkyl-9-BBN, prepared by hydroboration of alkenes with 9-BBN-H) to alkynoates to form β-disubstituted acrylates is reported. The addition occurred in a formal syn-hydroalkylation mode. The syn stereoselectivity was excellent regardless of the substrate structure. A variety of functional groups were compatible with the conjugate addi...