Retinal damage is an optional sign in a number of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). The aim this work was to assess the structural and functional state retina murine model ALS caused by overexpression aberrant FUS protein [1-359]. retinal examination carried out on 12 transgenic 13 wild-type mice 2.5–3 months age. study revealed not statistically signifi...

We present an automated numerical method of compensating for retinal shadows in the choroid. In this method, signal extinction caused by retinal vessels is estimated by subtracting median A-scans obtained from beneath the retinal vessels and A-scans from the surrounding area. Adding the obtained offset vector to A-scans from beneath the retinal vessels allows compensating for shadows in the cho...

Angiogenesis, the growth of new vessels from pre-existing blood vessels, requires complex signaling pathways and a high degree of spatial and temporal coordination among various cell types, multiple proand anti-angiogenic factors, and their corresponding receptors. Although the targeted disruption of many of these factors leads to embryonic lethal defects in vascular development, the precise ac...

Purpose: Characterization of the D-glucose tnnsport acms isolated normal and diabetic rabtnt retmal vessels wing " in vitro " lriicmpxfusicm techniques. Methods: After manual dissection and caonulation of normal and diabetic retinal vessels, they were penis4 with %D-gluar;e and 'H-inulin and studied under different cqcrimental conditions. Results We observed in normal retinal vessels a signific...

PURPOSE To assess the role of astrocytes in controlling the growth of developing retinal vessels. METHODS Growth of retinal vessels in the neonatal rat retina was examined in three conditions: normal development, cyclic hyperoxia, and normoxia (1 day 70% to 75% oxygen, 1 day room air for up to seven cycles from birth, and room air for up to 16 days), and direct hypoxia (10% oxygen from postna...

Objective. This study aimed to determine the influence of Tang Wang One Decoction (TWOD) on the retinal vessels of diabetic rats. Methods. The hemorheology of diabetic rats was observed. Morphological studies of retinal vessels were conducted using optical microscopy and electron microscopy. Immunological histochemistry assay was used to measure the expression levels of MMP-9, occludin, and cla...