The microstructure evolution characteristics and the shear strength of bond base alloys were investigated during press bonding Ti–5Al–2Sn–2Zr–4Mo–4Cr alloy. quantitative detection interfacial void shows that voids shrunk gradually with time a free could be obtained at above 10 min. alloy primary α phase tends to equiaxed because increase in plastic deformation variation volume fraction grain si...

On the basis of our recently resolved first cocrystal structure of Mdm4 in complex with a small molecule inhibitor (PDB ID 3LBJ ), we devised an approach for the generation of potential Mdm4 selective ligands. We performed the Ugi four-component reaction (Ugi-4CR) in 96-well plates with an indole fragment, which is specially designed to mimic Trp23, a key amino acid for the interaction between ...

The effect of a two-step heat treatment on the microstructure and high-temperature tensile properties ?-containing Ti-44Al-4Cr (at%) alloys fabricated by electron beam powder bed fusion were examined focusing morphology ?2/? lamellar grains ?/? cells precipitated at grain boundaries cellular precipitation reaction. subjected to first step 1573 K in ? + ? two-phase region exhibit non-equilibrium...