general sound in principle, some of it curiously unaltered since the days of Theodoric and Johannes de Mirfeld. Evidently a seventeenth-century neurosurgeon kept his fingernails long in readiness for the removal of an exposed pericranium. The selected case histories of Scultetus (23 out of the 100 concern the skull and brain) make interesting reading showing a conservative approach to treatment...

potent, long-lasting b2-adreoceptor agonist effects. Clinical studies have revealed that it induces bronchodilation for at least 12 h after a single oral administration. However, in order to maintain effective plasma concentrations and suppress asthmatic fits, there is considerable interest in development of transdermal drug delivery systems. Transdermal drug delivery is well recognized as an a...

A historiographical analysis of the events Petrine era in Caucasus demonstrates that problem personal contacts Tsar Peter I with ruling elites Dagestan during his campaign 1722 remains one poorly developed historical aspects. The tsar’s foreign were part imperial policy expanding territories Russian state, involving new subjects sphere political and legal space empire, ensuring their loyalty co...

A number of publications have been devoted to the Persian campaign Peter Great and stay Russian Imperial troops on southwestern shores Caspian Sea in 1722–1735 – monographs, articles, dissertations, collections documents materials prepared with use a wide range sources literature. This topic continues attract attention historians even today. It has acquired particular relevance connection 350th...

patients and methods in this cross-sectional study, peripheral mononuclear cells (pbmcs) were isolated from peripheral blood of 29 patients with newly diagnosed pulmonary tb and 19 patients with positive tuberculin skin test. the pbmcs were activated with ppd for 72 hours. activated cells were harvested, rna was extracted and cdna was synthesized. a real-time taqman method was designed and opti...