BACKGROUND Circular RNAs are a subgroup of non-coding RNAs and generated by a mammalian genome. Herein, the expression and function of circular RNA circ-TTBK2 were investigated in human glioma cells. METHODS Fluorescence in situ hybridization and quantitative real-time PCR were conducted to profile the cell distribution and expression of circ-TTBK2 and microRNA-217 (miR-217) in glioma tissues...

Çalışmamızda Hz. Peygamber’in hicretine dair bir değerlendirme yapılmıştır. Hicret bütün yönleriyle ele alınmamış olup Peygamber ve Ebu Bekir’in Sevr Mağarası’na çıkışı, Ali’nin yatağında yatması buna rivayetlerle sınırlı tutulmuştur. Ayrıca yatmasına bazı rivayetlerin meydana getirdiği problemlere dikkat çekilmiştir. cesaret fedakârlığıyla ilişkilendirilen olayın açısından sakıncalar ise rivay...

MicroRNA (miR)-217 has been reported to participate in carcinogenesis and tumor progression in several cancers; however, its expression and biological functions in colorectal cancer (CRC) are still unclear. The present study demonstrated that miR-217 expression was significantly higher in matched adjacent noncancerous tissues than in CRC tissues (P<0.001). In addition, it was observed that low-...

printing supported by Chiesi Farmaceutici SpA. Visit Chiesi Farmaceutici SpA. at Stand B.40 Thematic Poster Session Hall A-29 12:50-14:40

Up states are prolonged membrane potential depolarizations critical for synaptic integration and action potential generation in cortical and striatal neurons. They commonly result from numerous concurrent synaptic inputs, whereas neurons reside in a down state when synaptic inputs are few. By quantifying the composition, frequency, and amplitude of synaptic inputs for both states, we provide im...

A torsion pendulum without a torsion wire has been designed and realized, in order to measure very weak forces. The arm of this torsion pendulum ~5.40 g, 1.32310 kg m of inertia! is electrostatically suspended. Its 6 degrees of freedom are controlled thanks to electrostatic forces, and capacitive position sensing with a noise spectral density between 10 and 10 m/AHz. The torque noise spectral d...