نتایج جستجو برای: 17b
تعداد نتایج: 472 فیلتر نتایج به سال:
The formylpeptide receptors (nomenclature agreed by the NC-IUPHAR Subcommittee on receptor family [196]) respond to exogenous ligands such as bacterial product fMet-Leu-Phe (fMLP) and endogenous lipoxin A4 (LXA4), 15-epi-lipoxin A4, annexin I , cathepsin G, amyloid β42, serum A spinorphin, derived from β-haemoglobin. FPR1 also serves a plague for selective destruction of human immune cells Y. p...
Interplay between IL-17 family members and angiogenic cytokines in subjects with systemic sclerosis.
Introduction Systemic sclerosis (SSc) is a chronic, autoimmune connective tissue disease characterized by immune system activation, vasculopathy, and collagen accumulation. Despite progressive fibrosis of the vasculature, compensatory angiogenesis impaired. The cause shift towards anti-angiogenesis observed in SSc unknown. IL-17 cytokine family participates pathogenesis angiogenesis. Material m...
Oral contraceptives remain a popular method of contraception over 50 years after their introduction. While safe and effective for many women, the failure rate of oral contraception is about 8%. Concerns about the risk of venous thromboembolism continue to drive the search for the safest oral contraceptive formulations. The oral contraceptive NOMAC-E2 contains nomegestrol acetate (NOMAC) 2.5 mg ...
Interleukin (IL)-25, a cytokine active in inflammatory processes and production of proinflammatory cytokines, is secreted by mammary epithelial non-malignant cells and induces apoptosis in tumour cells by differential expression of its receptor IL-17RB, highly expressed in malignant cells and lower expressed in non-malignant epithelial cells. It is known that another ligand (IL-17B) compete for...
Noris, Marina, Marta Todeschini, Sergio Zappella, Samantha Bonazzola, Carla Zoja, Daniela Corna, Flavio Gaspari, Franco Marchetti, Sistiana Aiello, and Giuseppe Remuzzi. 17b-Estradiol corrects hemostasis in uremic rats by limiting vascular expression of nitric oxide synthases. Am J Physiol Renal Physiol 279: F626–F635, 2000.—Conjugated estrogens shorten the prolonged bleeding time in uremic pat...
We recently derived a CD4-independent virus from HIV-1/IIIB, termed IIIBx, which interacts directly with the chemokine receptor CXCR4 to infect cells. To address the underlying mechanism, a cloned Env from the IIIBx swarm (8x) was used to produce soluble gp120. 8x gp120 bound directly to cells expressing only CXCR4, whereas binding of IIIB gp120 required soluble CD4. Using an optical biosensor,...
Polycystic ovary syndrome (PCOS), characterized by chronic anovulation, hyperandrogenemia, obesity, central adiposity, and insulin resistance (1–3), represents a unique, natural model for study of the influences of androgenic hormones on bone mass among women. PCOS usually manifests at puberty and is currently recognized as one of the most common endocrine disorders among women of reproductive ...
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