Background: IKAROS, encoded by Ikaros Family Zinc Finger 1 (IKZF1), is a zinc finger transcription factor and critical regulator of hematopoiesis. We previously found that human epidermis expressed IKZF1. In addition, we generated K5-Ikzf1-EGFP transgenic mice (Ikzf1 Tg) introducing the IKZF1 isoform into cells expressing keratin 5 which developed dermatitis also patchy alopecia. A previous in ...