ALTERED MORPHOLOGY AND COMPOSITION OF ZYMOGEN GRANULES INACUTE PANCREATITISby AMANDA FLACKAugust 2014Advisor: Dr. Bhanu JenaMajor: PhysiologyDegree: Doctor of PhilosophyIn healthy physiology, pancreatic digestive enzymes secreted following a meal are storedas inactive zymogens within membrane-bound secretory vesicles called Zymogen Granules(ZG), and activ...

The effects of prolonged (7-day) ACTH and dexamethasone administrations on rat adrenocortical-cell turnover have been investigated by combined stereological and metaphase-arrest techniques. ACTH was found to increase the number of parenchymal cells in each adrenal zone; however, ACTH altered the cell distribution in the cortex, lowering their percentage in the zona glomerulosa (ZG) and zona fas...

Evodiamine is a bioactive alkaloid extracted from a Chinese herb named Wu-Chu-Yu, which possesses thermoregulatory, analgesic, and cardiovascular effects. Some studies have demonstrated that evodiamine reduces blood pressure through acting on endothelium and smooth muscle cells to produce a vasodilatory effect, but whether it affects aldosterone secretion is unclear. The purpose of this study w...

The effects of endothelins (ET) on the proliferative activity of the rat adrenal cortex have been investigated in vivo, using an in situ perfusion technique of the intact left gland. The chemicals were dissolved in the perfusion medium, and the perfusion continued for 120 min. ET-1 concentration dependently increased the mitotic index and [3H]thymidine incorporation into DNA in the zona glomeru...

We study the ramifications of Schur’s theorem that, if G is a group such that G/ZG is finite, then G′ is finite, if we restrict attention to nilpotent group. Here ZG is the center of G, and G′ is the commutator subgroup. We use localization methods and obtain relativized versions of the main theorems. 2000 Mathematics Subject Classification. 20B07, 20D15.

INTRODUCTION. .................................................................. 559 Description of zigzag culms.. ...................................................... 560 Terminology ..................................................................... 560 Inheritance of zigzag culms.. ...................................................... 560 Behavior in the FI and FS generations.. ...........

Secretion of enzymes and fluid induced by Ca(2+) in pancreatic acini is not completely understood and may involve activation of ion conductive pathways in zymogen granule (ZG) membranes. We hypothesized that a chromanol 293B-sensitive K(+) conductance carried by a KCNQ1 protein is expressed in ZG membranes (ZGM). In suspensions of rat pancreatic ZG, ion flux was determined by ionophore-induced ...

ABSTRACT Zero-grazing (ZG; the mechanical harvesting and feeding of fresh grass) is increasingly used in grass-based milk production systems alongside conventional grazing. It allows farmers to supply grass from land parcels that are outside main grazing block during seasonal shortages periods when climatic conditions limit animal opportunities. The objective this study was establish an underst...