Resume of 'previous work.?Vaughan (1921) found that an aqueous infusion of the leaves of Vitex peduncularis, Wall, var. roxburghiana, was being used by the aboriginal tribe of Ranchi in malaria and blackwater fever. Though the medicinal properties of the members of the Vitex family (e.g. Vitex trifolia, negundo, etc.) have been elaborately described in the Ayurvedic system of medicine, the Vite...

In Côte d'Ivoire, the non-alcoholic beverage industry is gradually turning to fruits from local wild species. More and more products latter are entering market. Black plum, fruit of Vitex doniana, very pleasant rich in bioactive compounds, has been transformed into nectar without addition preservatives. As a result, this product remains subject possible alteration its nutritional quality reduct...

An extract from ripe fruit of Vitex agnus-castus (Vitex) has been used to treat patients with various obstetric and gynecological disorders in Europe. We have demonstrated that Vitex showed cytocidal effects on various types of cancer cell lines including a human colon carcinoma cell line, COLO 201. In this study, we extended our previous study to investigate the detailed mechanisms underlying ...

Food industry and more specifically that of juices in Côte d'Ivoire, is gradually turning to local fruits. New products, sometimes derived from wild fruit species, are appearing on the market. The savannah plum tree (Vitex doniana) hitherto undervalued, experiencing renewed interest due its socio-economic importance for populations. Its black fruit, rich bioactive compounds, has been semi-indus...

Background: Cardiovascular diseases (CVDs) constitute the number one cause of mortality at global level, representing 30% all deaths. Therefore, finding ways to reduce deaths due CVDs remain an important public health goal. Traditional healers in northern Nigeria use stem bark Vitex doniana treat hypertensive patients. This study was aimed investigate cardiocurative potential on doxorubicin-ind...

BACKGROUND Aging is associated with the loss of endocrine function. In this study, Vitex agnus-castus (Vitex), which has antioxidant effects and high levels of phytoestrogen, was investigated with regard to the hypothalamic-pituitary-gonadal axis and antioxidant indices in natural aging and in a d-galactose induced aging model in female mice. METHODS The mice were subcutaneously injected with...