Though vanadium complexes mimic the action of insulin, owing to their toxicity, research is still in progress for a new vanadium complex with maximum efficacy at low concentration and without any side effects. A novel macrocyclic binuclear oxovanadium complex was synthesized, its composition and structure were confirmed by spectral studies and its efficacy was studied in streptozotocin-induced ...

Thiolate complexes continue to attract considerable attention due to their unique chemical properties and structural diversity. Since thiolate groups meet the electronic and steric requirements necessary to stabilize a wide variety of metal complexes, they have been used as auxiliary ligands. On the other hand, thiolate complexes are known to undergo chemistry at the sulfur center, including ox...

Formation equilibria of dioxy vanadium (V) complex with alanine in acidic media (pH<2.3) has been investigated potentiometrically and spectrophotometrically. In this condition the 1:1 complex has the formula VO2Y, where Y¯ represent the fully dissociated aminocarboxylate anion. The stability constant of VO2Y was determined as log KVO2Y=11.32±<e...

Vanadium is special in at least two respects: on the one hand, the tetrahedral anion vanadate(v) is similar to the phosphate anion; vanadate can thus interact with various physiological substrates that are otherwise functionalized by phosphate. On the other hand, the transition metal vanadium can easily expand its sphere beyond tetrahedral coordination, and switch between the oxidation states +...

Metal-catalyzed halogenation of the C-H bond and decarbonylation of aldehyde are conventionally done in nature. However, metal-mediated decarbonylative halogenation is unknown. We have developed the first metal-mediated decarbonylative halogenation reaction starting from the divanadium oxoperoxo complex K3V(5+)2(O2(2-))4(O(2-))2(μ-OH) (1). A concerted decarbonylative halogenation reaction was p...

Diabetes patients suffer from chronic disorders in the metabolism due to high blood sugar caused by anomalies in insulin excretion. Recently, vanadium compounds have been prepared and functionalized to decrease the level of hyperglycemia. Vitamin A boosts beta cell activity; therefore, the lack of this vitamin plays a role in the development of type 2 diabetes. The aim of this article focused o...

The stoichiometry and thermodynamic stability of vanadium(IV/V) complexes of Triapine and two related α(N)-heterocyclic thiosemicarbazones (TSCs) with potential antitumor activity have been determined by pH-potentiometry, EPR and (51)V NMR spectroscopy in 30% (w/w) dimethyl sulfoxide/water solvent mixtures. In all cases, mono-ligand complexes in different protonation states were identified. Dim...

The aim of this thesis is the investigation of the spectroscopic properties and the electronic structure of vanadium in minerals with a geological and/or technological interest. V K-edge HERFD-XAS experiments were combined with a theoretical determination of the measured spectra. Two approaches were complementary used to calculate the spectra: an ab initio approach and a multielectronic one. Th...

A simple and highly selective spectrophotometric method has been developed for the determination of trace amounts of V (V) using newly synthesized reagent 5-bromo salicylaldehyde isonicotinoyl hydrazone (5BrSAINH) in aqueous DMF medium. Vanadium (V) forms a brown colored soluble complex with 5-BrSAINH in the pH range 1.0-5.0. The complex shows maximum absorbance at 400nm in the pH range 4.5-5.5...