In 2012, a novel coronavirus associated with severe respiratory disease in humans emerged in the Middle East. Epidemiologic investigations identified dromedary camels as the likely source of zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Here we provide experimental support for camels as a reservoir for MERS-CoV. We inoculated 3 adult camels with a human isola...

OBJECTIVES To identify the occurrence of upper respiratory tract infections (URTI), diarrheal diseases and trauma during the Haji season, and the practice of some preventive measures by pilgrims. METHODS A cohort study during November and December 2009 among hajjis registered while visiting Primary Health Care Centers of Riyadh, Kingdom of Saudi Arabia to get mandatory meningococcal meningiti...

BACKGROUND Bacterial colonization and recurrent infections of the respiratory tract contribute to the progression of chronic obstructive pulmonary disease (COPD). There is evidence that exacerbations of COPD are provoked by new bacterial strains acquired from the environment. Using a murine model of colonization, we examined whether chronic exposure to cigarette smoke (CS) promotes nasopharynge...

Respiratory syncytial virus (RSV), the major cause of lower respiratory tract disease in infants, is thought to infect the upper airways before spreading to the lower respiratory tract. A rhesus monkey model of RSV infection after upper airway inoculation was used to test the protective effect of intranasal treatment with HNK20, a mouse monoclonal IgA antibody against RSV F glycoprotein. HNK20 ...

this study was undertaken to define the prevalence of the upper gastrointestinal (gi) lesions, dyspeptic symptoms, h.pylori infection, and the impact of duration of dialysis on upper gi symptoms and lesions of children with end-stage renal disease. we studied 69 children with esrd who were under regular hemodialysis therapy in our department. the age of the patients were between 4-18 years (mea...

Aims. To document the antibiotic prescribing rate for upper respiratory tract infections (URTI) in general practice and its associated factors. Methods. Data extracted from a morbidity survey of 150 general practice clinics in three urban areas in Malaysia. Participating general practitioners recorded demographic, morbidity and process of care data for 30 consecutive adult patients using a stru...

Introduction Feline upper respiratory tract disease (FURTD) is also known as feline upper respiratory infection or “cat flu”. FURTD is caused by several agents and a common problem in kitten and young cats, especially in multi-cat households, e.g. animal shelters. Upper respiratory infections in cats are one of the leading causes of euthanasia in these environments. Transmission is facilitated ...

Coronavirus is a common cause of upper respiratory tract infection in children and has also been occasionally associated with lower respiratory tract infections. Use of reverse transcriptase polymerase chain reaction has aided in the rapid and reliable detection of these viruses, and thus has led to identification of these viruses as etiology of respiratory disease in more cases. We here presen...