BACKGROUND During October 2011 several residents and staff members at a long-term care facility (LTCF) for elderly fell ill with respiratory symptoms. Several of the residents required hospitalization and one died. Non-typeable Haemophilus influenzae (NTHi) was identified as the causative pathogen. METHODS A descriptive analysis of the outbreak and countermeasures was performed. For each iden...

background and objective: haemophilus influenzae type b (hib) is divided into two distinct genotypes, type i and type ii, based on the structure of capsular polysaccharides. the capsulation locus of haemophilus influenzae type b consists of three functionally distinct regions, designated regions 1 to 3. region iii contains hcsa and hcsb genes; however, notable sequence variation in this region ...

Background: Haemophilus influenzae β-lactam resistance is mediated by production of β-lactamase and mutations in penicillin-binding protein 3 (PBP3, encoded ftsI). Only one the 646 patient-unique H. isolated our laboratory between 2012–July 2022 was meropenem (amoxicillin, co-amoxiclav ceftriaxone) resistant. Methods: Identification susceptibility this meropenem-resistant (MRHI) confirmed disk ...

A recently published paper that assessed the comparative cost-effectiveness of the 2 pneumococcal conjugate vaccines (PCVs) in Malaysia and Hong Kong reported that the 13-valent PCV vaccine (PCV13) is a better choice compared to the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV or PCV10) from both a payer and societal perspective as well as unde...

Non-typeable Haemophilus influenzae (NTHi) is a major cause of mucosal infections such as otitis media, sinusitis, conjunctivitis, and exacerbations of chronic obstructive pulmonary disease. In some regions, a strong causal relation links this pathogen with infections of the lower respiratory tract. In the past 20 years, a steady but constant increase has occurred in invasive NTHi worldwide, wi...

guillain barre syndrome (gbs) is an inflammatory, usually demyelinating, polyneuropathy; clinically characterized by acute onset of symmetric progressive muscle weakness with loss of myotatic reflexes. thirty five patients with gbs, defined clinically according to the criteria of asbury and cornblath, were recruited from three hospital affiliated to tehran university of medical sciences.as a co...