The turn-by-turn directions provided in existing navigation applications are exclusively derived from underlying road network topology information, i.e., the connectivity of edges to each other. Therefore, the turn-by-turn directions are simplified as metric translation of physical world (e.g. distance/time to turn) to spoken language. Such translation that ignores human cognition of the geogra...

Mimetics of secondary structure elements are one promising approach in the design of protein-protein interaction inhibitors, since secondary structure elements are very important recognition motifs in protein-protein interfaces. In helices and turns, the protein backbone provides a scaffold to present the sidechains in the correct orientation for the three-dimensional interaction motif. For bot...

As typical turn by turn systems fail in several aspects to provide an engaging experience to pedestrians in urban environments, we investigate the potential of alternative interaction methods for navigation. We present a two-phase experiment, involving both audio and tactile navigation and discuss the collected evaluation data. Our findings show a positive reception of implicit navigation from ...

Nonlinear field is of importance for the design and operation of circular machines and nonlinear beam dynamics has been intensively investigated both theoretically and experimentally [1]. Theoretically, nonlinear elements are designed on purpose to assist the operation of the machines e.g., the correction of the chromatic aberration and/or slow extraction with the help of sextupole magnets, the...

Navigation systems allow to discover cities and their urban areas easily and quickly, finding the shortest path to reach them and giving directions to users saving their time and energy. At present time, these systems are based over streets maps offered by the major mapping services like Tele Atlas, Navteq or OpenStreetMap. In recent years, thanks to the Google StreetView service it has been po...

amyloid-β (aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in alzheimer’s disease pathology.uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...