نتایج جستجو برای: tox

تعداد نتایج: 724  

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2017
Daland R Juberg Thomas B Knudsen Miriam Sander Nancy B Beck Elaine M Faustman Donna L Mendrick John R Fowle Thomas Hartung Raymond R Tice Emmanuel Lemazurier Richard A Becker Suzanne Compton Fitzpatrick George P Daston Alison Harrill Ronald N Hines Douglas A Keller John C Lipscomb David Watson Tina Bahadori Kevin M Crofton

Future Tox III, a Society of Toxicology Contemporary Concepts in Toxicology workshop, was held in November 2015. Building upon Future Tox I and II, Future Tox III was focused on developing the high throughput risk assessment paradigm and taking the science of in vitro data and in silico models forward to explore the question-what progress is being made to address challenges in implementing the ...

Journal: :The EMBO Journal 2015

Journal: :Obesity Surgery 2019

Journal: :Mutation research 2004
Larry D Kier Robin Neft Lei Tang Robert Suizu Tari Cook Kathy Onsurez Karen Tiegler Yumiko Sakai Michael Ortiz Tim Nolan Usha Sankar Albert P Li

Microarrays with toxicologically relevant genes (tox genes) have been developed in our laboratory for toxicogenomics studies in rat, dog and man. The genes were chosen using published information as well as a discovery process for genes responsive to toxic treatments using transcription profiling experiments conducted with rats and dogs. In addition to published information human tox genes were...

1996
Chenming Hu

MOSFET gate oxide scaling limits are examined with respect to time-dependent breakdown, defects, plasma process damage, mobility degradation, poly-gate depletion, inversion layer thickness, tunneling leakage, charge trapping, and gate delay. It is projected that the operating field will stay around 5MV/cm for reliability and optimum speed. Tunneling leakage prevents scaling below 2nm, which is ...

Journal: :Cytogenetic and genome research 2002
T Goldammer E Owens R M Brunner S R Kata J E Womack M Schwerin

Syndecan 2 gene codes for a transmembrane heparan sulfate proteoglycan protein that has an unclear function at the cell surface. The tumorigenic activity of SDC2 in colon carcinoma cell behavior and its influence on the regulation of adhesion and proliferation in colon carcinoma cell has been described (Park et al., 2002). TOX represents a thymus high mobility group box protein that is involved...

Journal: :iranian journal of parasitology 0
horaţiu alexandru colosi dept. of medical informatics and biostatistics, “iuliu haţieganu” university of medicine and pharmacy, cluj-napoca, romania babak jalali-zadeh dept. of urology, municipal hospital, dej, romania ioana alina colosi dept. of microbiology, “iuliu haţieganu” university of medicine and pharmacy, cluj-napoca, romania laura mihaela simon dept. of microbiology, “iuliu haţieganu” university of medicine and pharmacy, cluj-napoca, romania carmen anca costache dept. of microbiology, “iuliu haţieganu” university of medicine and pharmacy, cluj-napoca, romania

background: this study was conducted to investigate the influence of toxoplasma gondii infection on spermatic and hormonal parameters in a pilot sample of immunocompe­tent human male subjects. methods: this cross sectional, observational pilot study on 60 immunocompetent hu­man male subjects aged between 18 and 60 yr old was conducted between 2012 -2013. blind evaluation of serological markers ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2001
N Mani B Dupuy

Clostridium difficile, a causative agent of antibiotic-associated diarrhea and its potentially lethal form, pseudomembranous colitis, produces two large protein toxins that are responsible for the cellular damage associated with the disease. The level of toxin production appears to be critical for determining the severity of the disease, but the mechanism by which toxin synthesis is regulated i...

Journal: :The Journal of Experimental Medicine 2008
Parinaz Aliahmad Jonathan Kaye

CD8(+) cytotoxic and CD4(+) helper/inducer T cells develop from common thymocyte precursors that express both CD4 and CD8 molecules. Upon T cell receptor signaling, these cells initiate a differentiation program that includes complex changes in CD4 and CD8 expression, allowing identification of transitional intermediates in this developmental pathway. Little is known about regulation of these e...

Journal: :Stroke 2010
Christian Zweifel Gianluca Castellani Marek Czosnyka Emmanuel Carrera Kenneth M Brady Peter J Kirkpatrick John D Pickard Peter Smielewski

BACKGROUND AND PURPOSE In patients with subarachnoid hemorrhage, the assessment of cerebral autoregulation aids in prognosis as well as detection of vasospasm. Mx is a validated index of cerebral autoregulation based on measures of cerebral perfusion pressure and mean flow velocity on transcranial Doppler but is impractical for longer-term monitoring. Near-infrared spectroscopy is noninvasive a...

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