The present study was aimed at verifying whether serum L-fucose, total sialic acid (TSA) and ceruloplasmin can be used as prognostic indicators for type II diabetes mellitus, which will help in detecting complications of diabetes at an earlier stage. Thirty confirmed type II diabetic patients and 30 non-diabetic subjects were considered for the study. Serum L-fucose, total sialic acid and cerul...

Background: Increased levels of total and lipid-associated sialic acid (TSA and LASA) have been reported in the sera of patients with benign or malignant tumors and also could be regarded as newly important clinical criteria for the diagnosis of cancer. This study has investigated the differences of TSA and LASA contents between cancer patients and healthy individuals and evaluated their correl...

OBJECTIVE To determine whether serum sialic acid concentration may be used to predict short and long term cardiovascular mortality. DESIGN Prospective study on all men and women who had their serum sialic acid concentration measured as part of a general health survey in 1964 or in 1965. All were followed up for an average of 20.5 years. SETTING Geographical part of the county of Värmland, S...

Current methods for analyzing sialic acid diversity in modifications and linkages require multistep processing, derivatization, and chromatographic analyses. We here report a single-step optical method for identification and quantification of different compositions of sialoglycans on glycoproteins and in serum. This was achieved by measuring and quantifying nanometal surface energy transfer (NS...

The surface of vascular endothelium bears a glycocalyx comprised, in part, of a complex mixture of oligosaccharide chains attached to cell-surface proteins and membrane lipids. Importantly, understanding of the structure and function of the endothelial glycocalyx is poorly understood. Preliminary studies have demonstrated structural differences in the glycocalyx of pulmonary artery endothelial ...

OBJECTIVE The aim of this study was to analyze some standard parameters of the unstimulated and stimulated whole saliva of mouth-breathers and a control group to determine if these variables present any difference in mouth-breathers compared to control group, since these parameters of saliva can influence the oral health. METHODS Saliva samples were collected from 61 adolescents aged 10-19 ye...

background: increased levels of total and lipid-associated sialic acid (tsa and lasa) have been reported in the sera of patients with benign or malignant tumors and also could be regarded as newly important clinical criteria for the diagnosis of cancer. this study has investigated the differences of tsa and lasa contents between cancer patients and healthy individuals and evaluated their correl...

two sialic acid specific lectins episesarma tetragonum agglutinin–1 and 2 were purified from the hemolymph of the mangrove crab, episesarma tetragonum . the major lectin was purified using cnbr-activated sepharose 4b conjugated to fetuin. n-acetyl glucosamine containing buffer was used for elution. the hemagglutination activity of purified lectin was inhibited by glycoproteins containing siaα, ...

changed, whereas hexosamine values were gradually increased and seemed to be correlated to total cell count, but not to the count of adhered cells on the glass wall. On the other hand, hexosamine and sialic acid contents of both the cells adhering to the glass wall were determined after washing with saline solution. The results are given in Table I. No remarkable difference in hexosamine and si...