The genus Tinospora includes 34 species, in which several herbs were used as traditional medicines by indigenous groups throughout the tropical and subtropical parts of Asia, Africa, and Australia. The extensive literature survey revealed Tinospora species to be a group of important medicinal plants used for the ethnomedical treatment of colds, headaches, pharyngitis, fever, diarrhea, oral ulce...

Guduchi also known as having heart shaped leaves, belongs to family Menispermaceae native Indian subcontinent. The aqueous and methanol stem extract of is being used for their Immunomodulatory activity they revive immune imbalance which helps in preventing healing many diseases. intensively studied its immunomodulating effects because wide-ranging uses treating diseases related system indigenou...

The safety of Tinospora cordifolia and its potential to protect against ultraviolet radiation-induced cytotoxicity and DNA damage in PC12 cells were investigated. To evaluate the safety of T. cordifolia, cell viability and agarose gel electrophoresis were carried out using PC12 cells treated with 0 to 100 μg mL(-1) of methanol extract of T. cordifolia. T. cordifolia extracts did not show cytoto...

In our classical Ayurvedic texts, it has been described as beneficial in treating various types of diseases. Tinospora cordifolia satva (TCS) and ghana (TCG) is one the unique Ayuvedic preparations, prepared from aqueous extract Giloy (Tinospora Miers.) stem. These are frequently used medicines for treatment Madhumeha, Pandu, Kamala, Amlapitta, Grahani, Kustha, Jirna Jwara Viswamjwara, Trishna,...

Tinospora cordifolia (Willd.) Hook.f. & Thomson is a climbing deciduous shrub. It is found throughout tropical part of India also found in China, Bangladesh, Myanmar and Srilanka. Plant refers wide range of soil, acid to alkaline and it needs moderate moisture level. In Ayurveda, basically it is used for its general adaptogenic, rejuvenating and immunomodulatory activity. Besides of these prope...

Pseudomonas aeruginosa and Acinetobacter baumannii are common nosocomial pathogens, well recognized for their multidrug resistance. Acyl-homoserine lactone (Acyl-HSL) based Quorum sensing (QS) is known to regulate virulence and biofilm maturation in these organisms; hence, inhibition of QS will help to control their pathogenicity. In the study, 5 plants, Rubia cordifolia, Tinospora cordifolia, ...

Ayurveda is one of the oldest systems medicine in world. There are almost 1200 plants mentioned for their medicinal properties. Thus, Pharma therapeutics mainly centered on use various plant parts management innumerable diseases. Guduchi (Tinospora cordifolia (Willd.) Hook. F. & Thoms.) Is such praise widely its efficacy treatment diseases along with superior rejuvenation property? Ayurvedic ph...

The present study investigated the antiarrhythmic activity of alcoholic extract of Tinospora cordifolia (T. cordifolia) in CaCl2 induced arrhythmia. CaCl2 (25 mg/kg) was administered by intravenous infusion (iv) to produce arrhythmia in rats. The animals were then treated with T. cordifolia extract (150, 250, and 450 mg/kg) and verapamil (5 mg/kg,iv). Lead II electrocardiogram was monitored. Pl...

INTRODUCTION Pain is a very well-known signal of ill health and analgesics are the drugs that are used to relieve pain. The main problem with these drugs remains that of side effects. Safer alternatives are natural herbs. Guduchi (Tinospora cordifolia) is one such plant with analgesic potential but few studies are there. OBJECTIVE To evaluate the analgesic activity of commercially available e...

Phytochemical investigation of the chloroform extract of Tinospora cordifolia yielded a new clerodane diterpenoid tincordin along with tinosporide, 8-hydroxytinosporide, columbin, 8-hydroxycolumbin and 10-hydroxycolumbin. The structure of the new compound was elucidated comprehensively using 1D and 2D NMR methods. All major clerodane diterpenoids isolated were tested for their efficacy as insec...