Mortality rates for fulminant hepatic failure range between 50% and 90%. Several independent factors influence survival: age, etiology, depth and duration of the encephalopathy, and prevention of complications. The main causes of fulminant hepatic failure are hepatotropic viruses, adverse drug effects, and toxins (Table 1). All major hepatotropic viruses can induce fulminant hepatic failure. We...

1. Steinhubl SR, Berger PB, Mann JT III, et al. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial. JAMA 2002;288:2411–20. 2. Mehta SR, Yusuf S, Peters RJG, et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE st...

Implantation failure is the most frequent cause of pregnancy loss in couples who try to conceive, either in a natural way or using assisted reproductive techniques (ART). Identify the precise mechanisms of implantation failure can lead to identify couples at risk and also providing appropriate therapeutic options to affected couples. Despite the high prevalence of this disorder, a few causing f...

Heart failure statistics are daunting: 550,000 new cases each year, a 1-year mortality rate of nearly 20%, and annual direct and indirect costs that total $24.3 billion.1 The diverse etiology of heart failure and the complex, progressive course of the disease can make treatment decisions daunting as well. Here I discuss current recommendations for heart failure management, as well as the clinic...