Under conditions of high pulmonary artery pressure and flow produced in dogs by a controlled systemic artery shunt, pulmonary edema occurred after denervation of the lung at arterial pressures that were tolerated without edema before denervation. Left atrial pressures were not altered by the shunt, which involved only one segment of lung. Observation of animals with shunts for \],i to 10 months...

OBJECTIVE To analyze the initial results of the use of an organic tubular graft for systemic-pulmonary anastomoses. METHODS From March 2002 to April 2003, 10 patients underwent systemic-pulmonary shunt of the modified Blalock-Taussig type, using a new type of biological graft originating from the bovine mesenteric artery treated with polyglycol, the so-called L-D-Hydro. The patients' ages ran...

The Norwood-based strategy for single ventricle palliation has improved with technical innovations and refinements over the last decades; such as regional cerebral perfusion during aortic arch reconstruction [1], placement of a right ventricle-to-pulmonary artery (RV-PA) shunt rather than a systemic-to-pulmonary shunt [2, 3], and the concept of aggressive afterload reduction to maximise oxygen ...

was proposed by Carlon et al.1 in 1951. In 1954, Glenn and Patifio2 described a modification of this anastomosis by suturing the superior vena cava (SVC) directly to the right pulmonary artery (RPA). Theoretical hemodynamic advantages of this method of palliation, compared with operations anastomosing a systemic artery to pulmonary artery (Blalock-Taussig, Potts shunt), were increased pulmonary...

Extensive clinical use has now been made of the nitrous oxide test for the detection and localization of left-to-right circulatory shunts. On theoretical grounds the magnitude of such a shunt should be related to the systemic and pulmonary arteriovenous differences in nitrous oxide content measured early in the period of inhalation. In order to determine the validity of the nitrous oxide method...

A 58-year-old man experienced paradoxic air embolism with passage of air from the systemic venous to the systemic arterial circulation with subsequent stroke and death. No intracardiac shunt was present. Pulmonary fibrosis concomitant with severe pulmonary arterial hypertension appears to have been responsible for the air traversing the pulmonary capillary bed. This unusual outcome of a complic...

Ten patients with hypoplastic left heart syndrome underwent cardiac catheterization to assess the effectiveness of palliative surgery designed to prepare them for a modified Fontan procedure. The objectives of palliation were to establish unobstructed systemic blood flow, normalize pulmonary blood flow and pressure, and relieve pulmonary venous obstruction. In the first four patients, systemic ...

Extensive clinical use has now been made of the nitrous oxide test for the detection and localization of left-to-right circulatory shunts. On theoretical grounds the magnitude of such a shunt should be related to the systemic and pulmonary arteriovenous differences in nitrous oxide content measured early in the period of inhalation. In order to determine the validity of the nitrous oxide method...

BACKGROUND Aspirin (ASA) often is used to prevent thrombosis in infants with congenital heart disease after placement of a systemic-to-pulmonary artery shunt, but its effect on outcomes is unknown. METHODS AND RESULTS The present multicenter study prospectively collected data on 1-year postoperative rates of death, shunt thrombosis, or hospitalization age <4 months for bidirectional Glenn/hem...