Recent therapeutic advances have improved standard treatment for patients with newly diagnosed glioblastoma. Unfortunately, even with these improvements, only a fraction of patients derive significant benefit and experience prolonged survival. These findings are consistent with long-standing clinical and recent molecular evidence that subtypes of glioblastoma exist with differing survival rates...

Cure models are survival models basically developed to estimate the proportion of patients cured in a clinical trial. These models estimate the cured proportion and also the probability of survival. Cure models are a special type of survival analysis model where it is assumed that there are a proportion of subjects who will never experience the event and thus the survival curve will eventually ...

Purpose: To evaluate the effect of patients, tumor and treatment-related variables on survival in patients with T1T2 N0M0 squamous cell carcinoma of the larynx who treated with radical radiotherapy. Material and Methods: Eighty-three patients with T 1 T2N0M0 squamous cell carcinoma of the larynx were analysed. Patients were treated with initial opposed lateral fields to treat the primary and dr...

In population based cancer studies, cure is said to occur when the mortality in the group of cancer patients returns to the same level as that expected in the general population. The cure fraction is of interest to patients and also a useful measure when analyzing trends in cancer patient survival. Recently models have been introduced, so called cure fraction models, that estimates the cure fra...

patients with coronary artery disease and left ventricular dysfunction have high mortality with non surgical (medical) treatment. coronary artery bypass grafting improves survival and the quality of life. recently, revascularization without cardiopulmonary bypass has been presented as a viable alternative. the aim of this study was to survey the result of coronary artery bypass grafting with of...

Background and objectives: Angiogenesis is essential for tumor survival. Inhibiting angiogenesis could be a mechanism for hindering tumor development. Numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. In the present study, Crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesi...

BACKGROUND Triple valve surgery (TVS) is still of choice for advanced rheumatic heart disease (RHD), which has been associated with reported poor early and late outcomes. We describe the short- and long-term results after TVS in last two decades in Mainland China. METHODS From January 1985 to January 2005, a total of 871 patients (217 men, 654 women), with mean age of 42+/-11 years, underwent...