نتایج جستجو برای: sperm telomere length
تعداد نتایج: 350309 فیلتر نتایج به سال:
Telomeres are structures at the ends of DNA strands that get longer in the DNA of sperm [2] cells as males age. That phenomenon is different for most other types of cells, for which telomeres get shorter as organisms age. In 1992, scientists showed that telomere [3] length (TL) in sperm [2] increases with age in contrast to most cell of most other types. Telomeres are the protective caps at the...
Previous studies have shown that both density gradient centrifugation (DGC) and swim up (SU) procedures can select spermatozoa with longer telomeres for assisted reproduction techniques (ART). However, it is unknown which approach is more effective. The aim of the present study was to compare the effects of these two methods on sperm telomere length (STL). A total of 150 normozoospermic subject...
BACKGROUND The incidence of atrial fibrillation (AF) increases with age. Telomere length is considered a marker of biological ageing. We investigated the association between leukocyte telomere length and incident AF in the Dutch Prevention of Renal and Vascular End-stage Disease (PREVEND) study. METHODS We included 7775 individuals without prevalent AF, and with leukocyte telomere length meas...
BACKGROUND Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telomere length. We investigated the importance of the early-life environment on both telomere tracking and adult telomere length. METHODS Among 184 twins of the East Flanders Prosp...
BACKGROUND Short telomere length independently predicts mortality in patients with coronary heart disease. Whether 5-year change in telomere length predicts subsequent mortality in patients with coronary heart disease has not been evaluated. METHODS In a prospective cohort study of 608 individuals with stable coronary artery disease, we measured leukocyte telomere length at baseline and after...
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