Depression is a disabling condition resulting in significant impairment in social functioning, involving the patient's family, friends, work colleagues, and society at large. Although both psychologic and pharmacologic treatments generally improve many depressive symptoms, they do not always result in significant improvement in social functioning. The importance of recovery of social functionin...

Depression and anxiety are prevalent mental health illnesses often diagnosed during the child adolescent years. Patients presenting with depression and/or symptoms typically initially present to a primary care provider (PCP). PCPs need be able identify symptoms, which can aided by screening tool. First-line treatment is psychotherapy followed selective serotonin reuptake inhibitor (SSRI) for th...

objective: major depression is a mood disorder that causes changes in physical activity, appetite, sleep and weight. regarding the role of zinc in the pathology of depression, the present study was aimed to investigate the effects of zinc supplementation in the treatment of this disease. methods: this study was a double-blind randomized clinical trial. forty four patients with major depression ...

this meta-analysis aims to assess the efficacy and safety of ssris and tcas in treatment of pd. a computer-base search was conducted of pubmed, medline, embase, cochrane controlled trails register (cctr) up to december 2011. the random controlled clinic trials about ssris and tcas in pd treatment were collected. statistical analysis was completed using review manager, version 5.0. five clinic c...

BACKGROUND AND PURPOSE Serotonin-specific antidepressants may increase the risk of adverse bleeding events. In a previous cross-sectional study, we did not observe an association between antidepressant use and presence of subclinical cerebral bleedings. In this study, we investigated longitudinally whether antidepressant use is associated with an increased risk of new subclinical cerebral micro...

Serotonin syndrome is a rare but potentially fatal adverse drug reaction associated with increased serotonergic activity in the central nervous system. It is characterized by a triad of symptoms, which include altered mental status, neuromuscular hyperactivity, and autonomic instability or hyperactivity. Due to the potential of rapid onset, it is important for clinicians to recognize the signs ...