نتایج جستجو برای: s retinoic acid

تعداد نتایج: 1400096  

2017
Szabolcs Tarapcsák Gábor Szalóki Ágnes Telbisz Zsuzsanna Gyöngy Krisztina Matúz Éva Csősz Péter Nagy Imre J. Holb Ralph Rühl László Nagy Gábor Szabó Katalin Goda

Retinoids - derivatives of vitamin A - are important cell permeant signaling molecules that regulate gene expression through activation of nuclear receptors. P-glycoprotein (Pgp) and ABCG2 are plasma membrane efflux transporters affecting the tissue distribution of numerous structurally unrelated lipophilic compounds. In the present work we aimed to study the interaction of the above ABC transp...

Journal: :journal of dentistry, tehran university of medical sciences 0
shamsolmoulouk najafi narges gholizadeh elahe akhavan rezayat mohammad javad kharrazifard

objectives: geographic tongue or migratory glossitis is an inflammatory disorder with unknown etiology. considering the accompanied burning pain, taste dysfunction, and lack of definite cure, it is important to treat this condition symptomatically. the objective of the current study was to compare the efficacy of a combination of 0.05% retinoic acid and 0.1% triamcinolone acetonide with that of...

Journal: :avicenna journal of medical biotechnology 0

background: mesenchymal stem cells (mscs) are multipotent cells that can be collected from different sources. under specific conditions, mscs can be differentiated to tissue specific cells in vitro. human umbilical cord mesenchymal stem cells (hucmscs) can easily be harvested and cultured in in vitro conditions. production of germ cells from mesenchymal stem cells is a very interesting and prom...

Journal: :iranian journal of blood and cancer 0
mahdi shahriari department of pediatrics, hematology-oncology branch, amir oncology hospital, shiraz university of medical sciences, shiraz, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (shiraz university of medical sciences) بابک عبدالکریمی babak abdolkarimi سازمان اصلی تایید شده: دانشگاه علوم پزشکی لرستان (lorestan university of medical sciences) fazl saleh department of pediatrics, hematology-oncology branch, amir oncology hospital, shiraz university of medical sciences, shiraz, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (shiraz university of medical sciences) pooria salajeghe department of pediatrics, hematology-oncology branch, aliasghar hospital, iran university of medical sciences, shiraz, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)

patients with acute myeloblastic leukemia (aml) with monosomy 7 are a group of patients with refractory aml who have a very poor prognosis. therefore, rationally designed new therapies, including metronomic chemotherapy regimen with histidine deacetylase inhibitors (valporic acid, atra) are being investigated as potential treatments for the population of refractory cases of aml. herein, we repo...

Journal: :cell journal 0

introduction: retinoic acid (ra), one of the syntetic vitamin a derivatives which has been frequently used as a drug to treat face acne, is known to have specific side effects on the testis, liver, and spleen, it is also known as an oxidative agent in high doses. therefore, we have tried to find a compound which would decrease its side effects. curcumin which is found in the rhizome of turmeric...

Bahman Zeynali, Hossein Baharvand, Masoud Soleimani, Reza Moghadasali,

Introduction: Embryonic Stem (ES) cells as pluripotent cells derived from the inner cell mass of blastula can differentiate to neural cells in vitro and this property is valuable in studies of neurogenesis and in the generation of donor cells for transplantation. In this regard, the propose of this research, was the study of the role of two important factors in the development of neural syst...

Journal: :international journal of reproductive biomedicine 0
maryam hosseinzadeh shirzeily parichehr pasbakhsh fardin amidi kobra mehrannia

background: recent publications about differentiation of stem cells to germ cells have motivated researchers to make new approaches to infertility. in vitro production of germ cells improves understanding differentiation process of male and female germ cells. due to the problem of using embryonic stem cells (esc), it’s necessary the mentioned cells be replaced with some adult multi-potent stem ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Leo M Y Lee Chun-Yin Leung Walfred W C Tang Heung-Ling Choi Yun-Chung Leung Peter J McCaffery Chi-Chiu Wang Adrian S Woolf Alisa S W Shum

Retinoic acid, an active metabolite of vitamin A, plays essential signaling roles in mammalian embryogenesis. Nevertheless, it has long been recognized that overexposure to vitamin A or retinoic acid causes widespread teratogenesis in rodents as well as humans. Although it has a short half-life, exposure to high levels of retinoic acid can disrupt development of yet-to-be formed organs, includi...

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