نتایج جستجو برای: retrotransposon

تعداد نتایج: 2306  

Journal: :The Plant journal : for cell and molecular biology 1999
S R Pearce C Stuart-Rogers M R Knox A Kumar T H Ellis A J Flavell

The terminal sequences of long-terminal repeat (LTR) retrotransposons are a source of powerful molecular markers for linkage mapping and biodiversity studies. The major factor limiting the widespread application of LTR retrotransposon-based molecular markers is the availability of new retrotransposon terminal sequences. We describe a PCR-based method for the rapid isolation of LTR sequences of ...

2008
Takashi Takabatake Hiroshi Ishihara Yasushi Ohmachi Izumi Tanaka Masako M. Nakamura Katsuyoshi Fujikawa Tokuhisa Hirouchi Shizuko Kakinuma Yoshiya Shimada Yoichi Oghiso Kimio Tanaka

Mammalian genomes contain numerous evolutionary harbored mobile elements, a part of which are still active and may cause genomic instability. Their movement and positional diversity occasionally result in phenotypic changes and variation by causing altered expression or disruption of neighboring host genes. Here, we describe a novel microarray-based method by which dispersed genomic locations o...

2016
Jenna Persson Babett Steglich Agata Smialowska Mette Boyd Jette Bornholdt Robin Andersson Catherine Schurra Benoit Arcangioli Albin Sandelin Olaf Nielsen Karl Ekwall

Retrotransposons, the ancestors of retroviruses, have the potential for gene disruption and genomic takeover if not kept in check. Paradoxically, although host cells repress these elements by multiple mechanisms, they are transcribed and are even activated under stress conditions. Here, we describe a new mechanism of retrotransposon regulation through transcription start site (TSS) selection by...

2011
Monica Laner Blauth Rafaela Vieira Bruno Eliana Abdelhay Vera Lúcia Silva Valente

Transposable elements (TEs) are mobile nucleotide sequences which, through changing position in host genomes, partake in important evolutionary processes. The expression patterns of two TEs, P element transposon and 412 retrotransposon, were investigated during Drosophila melanogaster and D. willistoni embryogenesis, by means of embryo hybridization using riboprobes. Spatiotemporal transcriptio...

2013
Katarzyna J. Purzycka David J. Garfinkel Jef D. Boeke Stuart F.J. Le Grice

The long-terminal repeat (LTR)-retrotransposon Ty1 is a mobile genetic element that replicates through an RNA intermediate. Retroelement genomic transcripts contain internal structures fundamental to gene expression and propagation. In addition, long non-coding antisense RNAs overlap the 5'-terminal region of the genomic RNA and confer post-translational copy number control. Although LTR- retro...

Journal: :Molecular biology and evolution 2004
Lucia F Franchini Eric W Ganko John F McDonald

We have surveyed 18 natural populations of Drosophila melanogaster for the presence of 23 retrotransposon-gene-association alleles (i.e., the presence of an LTR retrotransposon sequence in or within 1,000 bp of a gene) recently identified in the sequenced D. melanogaster genome. The identified associations were detected only in the D. melanogaster populations. The majority (61%) of the identifi...

Journal: :EMBO reports 2013
Jon Reinders Marie Mirouze Joël Nicolet Jerzy Paszkowski

Retrotransposons are ubiquitous mobile genetic elements constituting a major part of eukaryotic genomes. Yet, monitoring retrotransposition and subsequent copy number increases in multicellular eukaryotes is intrinsically difficult. By following the transgenerational accumulation of a newly activated retrotransposon EVADE (EVD) in Arabidopsis, we noticed fast expansion of activated elements tra...

Journal: :Genome research 2006
Benoit Piegu Romain Guyot Nathalie Picault Anne Roulin Abhijit Sanyal Hyeran Kim Kristi Collura Darshan S Brar Scott Jackson Rod A Wing Olivier Panaud

Retrotransposons are the main components of eukaryotic genomes, representing up to 80% of some large plant genomes. These mobile elements transpose via a "copy and paste" mechanism, thus increasing their copy number while active. Their accumulation is now accepted as the main factor of genome size increase in higher eukaryotes, besides polyploidy. However, the dynamics of this process are poorl...

Journal: :Cell reports 2017
Pedro Sousa-Victor Arshad Ayyaz Rippei Hayashi Yanyan Qi David T Madden Victoria V Lunyak Heinrich Jasper

Sophisticated mechanisms that preserve genome integrity are critical to ensure the maintenance of regenerative capacity while preventing transformation of somatic stem cells (SCs), yet little is known about mechanisms regulating genome maintenance in these cells. Here, we show that intestinal stem cells (ISCs) induce the Argonaute family protein Piwi in response to JAK/STAT signaling during acu...

Journal: :The Plant cell 2012
Eugenio Butelli Concetta Licciardello Yang Zhang Jianjun Liu Steve Mackay Paul Bailey Giuseppe Reforgiato-Recupero Cathie Martin

Traditionally, Sicilian blood oranges (Citrus sinensis) have been associated with cardiovascular health, and consumption has been shown to prevent obesity in mice fed a high-fat diet. Despite increasing consumer interest in these health-promoting attributes, production of blood oranges remains unreliable due largely to a dependency on cold for full color formation. We show that Sicilian blood o...

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