BACKGROUND Evidence-based medicine (EBM) has developed as the dominant paradigm of assessment of evidence that is used in clinical practice. Since its development, EBM has been applied to integrate the best available research into diagnosis and treatment with the purpose of improving patient care. In the EBM era, a hierarchy of evidence has been proposed, including various types of research met...

Evidence-based (science-based) care is the prevailing paradigm in the health sciences. This paper briefly reviews the basic concepts of evidence-based care. Assessment of scientific evidence including information retrieval, evaluation of the quality of evidence, and finally the synthesis of collected evidence is described. Practitioner approach to evidence-based care through the twin modalities...

The National Asthma Education and Prevention Program (NAEPP) keeps clinical practice guidelines up to date by identifying selected topics on asthma that warrant intensive review based on the level of research activity reflected in the published literature or the level of concern in clinical practice. The NAEPP Expert Panel identified key questions about asthma management and used a systematic r...

INTRODUCTION Despite widespread availability of clinical practice guidelines (CPGs), considerable gaps continue between the care that is recommended ('appropriate care') and the care provided. Problems with current CPGs are commonly cited as barriers to providing 'appropriate care'.Our study aims to develop and test an alternative method to keep CPGs accessible and up to date. This method aims ...

EASL–EORTC Clinical Practice Guidelines (CPG) on the management of hepatocellular carcinoma (HCC) define the use of surveillance, diagnosis, and therapeutic strategies recommended for patients with this type of cancer. This is the first European joint effort by the European Association for the Study of the Liver (EASL) and the European Organization for Research and Treatment of Cancer (EORTC) t...

Students and researchers might have diverse ideas about motivations for citizen science (CS) projects. To prevent uncertainty, we address ethical concerns emerging in CS projects general, specifically, the transferability of skills knowledge gained within academia (e.g. through studying research conduct). We dedicate these Guidelines Research Ethics Integrity Citizen Science primarily to Master...

background: the most common method of collecting data in any area of human health research is to apply a questionnaire. however, if extreme cautiousness is not taking into account while designing a questionnaire, the gathered data might be ineffective. therefore, the aim of the present article is to discuss some of the most important set of guidelines in designing a questionnaire.   materials a...