Aqueous conjugated polymer nanoparticles developed by nanoprecipitation from a quinoxaline–thiophene type with 3 fluorine atoms as potential cancer theranostics for breast cancer.

A series of quinoxaline-based compounds 1–4 have been synthesized by Palladium-Catalyzed cross-coupling reaction and their photophysical properties extensively studied. Compounds show deep blue light emission both in solution (λem ≤ 425 nm, CIEy≤0.03) solid-state. Moreover, 1–3 a non-typical aggregation-induced enhanced (AIEE), which would be effective light-emitting materials. The DFT calculat...

Photostable donor–acceptor–donor fluorophores, which have a central quinoxaline acceptor nucleus, been used in LSCs, obtaining outstanding results for modern building-integrated photovoltaics (BIPV).

2-Methylpyridinium trifluoromethanesulfonate ([2-MPyH]OTf) catalyzed synthesis of 1,5benzodiazepine and quinoxaline derivatives in the reaction of between o-phenylenediamine and ketone (synthesis of 1,5-benzodiazepine derivatives) or 1,2-diketone (synthesis of quinoxaline derivatives) in high yields and short time reaction. The catalyst can be separated from the products by a change in the solv...

The asymmetric unit of the title compound, C(16)H(14)N(2)O, contains three independent mol-ecules. The dihedral angles between the quinoxaline and phenyl planes in the three mol-ecules are 82.58 (8), 85.66 (9) and 85.36 (9)°. The crystal packing is stabilized by C-H⋯O and C-H⋯N hydrogen bonds.

In the title compound, C(14)H(9)BrN(2), the benzene and quinoxaline rings are almost coplanar [r.m.s. deviation = 0.0285 (3) Å and dihedral angle = 2.1 (2)°].

Quinoxaline antibiotics intercalate dsDNA and exhibit antitumor properties. However, they are difficult to synthesize and their structural complexity impedes a clear mechanistic understanding of DNA binding. Therefore design and synthesis of minimal-intercalators, using only part of the antibiotic scaffold so as to retain the key DNA-binding property, is extremely important. Reported is a uniqu...

In the mol-ecule of the title compound, C(19)H(17)ClN(2)O(4), the quinoxaline ring system is planar [maximum deviation = 0.013 (3) Å] and oriented at a dihedral angle of 80.18 (3)° with respect to the benzene ring. In the crystal structure, inter-molecular C-H⋯N inter-actions link mol-ecules into chains. π-π contacts between the quinoxaline systems [centroid-centroid distance = 3.654 (1) Å] may...

The asymmetric unit of the title quinoxaline compound, C(10)H(9)N(3)O(2), contains two crystallographically independent mol-ecules (A and B). The quinoxaline ring systems are essentially planar, with maximum deviations of 0.006 (1) and 0.017 (1) Å, respectively, for mol-ecules A and B. In mol-ecule A, the dihedral angle formed between the quinoxaline ring system and nitro group is 10.94 (3)° [6...