Cancer is characterized by uncontrolled cell growth, and the cause of different cancers is generally attributed to checkpoint dysregulation of cell proliferation and apoptosis. Recent studies have shown that non-optimal codons were preferentially adopted by genes to generate cell cycle-dependent oscillations in protein levels. This raises the intriguing question of how dynamic changes of codon ...

Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

Renal cell cancers are the most prevalent type of malign renal masses. Sarcomas are one of the rarest subtypes. Primary renal sarcomas make up 1e3% of all renal malign masses. Previously known as malign fibrosis histiocytoma (MFH), pleomorphic undifferentiated sarcoma (PUS) is the most prevalent soft tissue tumor in adults, with a 20% occurrence rate. PUS has a histologically wide range, the mo...

Oral cancer is one of the most prevalent cancers and one of the 10 most common causes of death in the world. Epidemiological studies have shown that the prevalence of oral cancer varies from less than 0.1% to over 40% in different parts of the world. Unfortunately, the majority of oral cancers are diagnosed in advanced stages after becoming symptomatic. In comparison with malignant neoplasms at...

Nanotechnology has revolutionized diagnosis and treatment of cancers. Breast cancer is oneof the most prevalent cancers among women. Paclitaxel and hydroxyurea are important drugsin treatment of breast cancer but their use is limited due to a series of significant side effects.On the other hand, nanoliposomes are widely used as nanocarriers for targeted drug delivery.In this study, cytotoxic ef...

Endometrial and cervical cancers are the most prevalent gynecologic neoplasms. While endometrial cancer occurs in older women, cervical cancer is more prevalente in young subjects. The most common clinical manifestation in these two gynecological cancers is vaginal bleeding. In the first case, diagnosis is made based on histological and imaging evaluation of the endometrium, while cervical canc...

BACKGROUND Urological cancers represent a major public problem associated with high mortality and morbidity. The pattern of these cancers varies markedly according to era, region and ethnic groups, but increasing incidence trends overall makes focused epidemiological studies important. The aim of the present study was to assess the incidence of most prevalent urological cancers in Iran from 200...

The average hospital bill for gynecologic cancers overall was almost $24,700—25 percent higher than the average U.S. hospital bill of $19,700. For ovarian cancer, the average bill was $35,200—nearly 80 percent higher than the average U.S. hospital bill (Figure 2). More than 1 in 3 American women develop cancer at some point in their lives. Over 40 percent1 of their diagnoses are associated with...