Poly(lactic acid) (PLA) and poly(lactic-coGA) (PLGA) with low molecular weights were synthesized by a one-step polycondensation of lactic acid (LA) with glycolic acid (GA) molecules using stannous octoate as a catalyst at 160°C. A high yield ( 80%) of all the polymers was obtained in the study. The PLA and PLGA copolymers were characterized by H-NMR, GPC, and DSC measurements, etc. We elaborate...

The effects of annealing on the mechanical properties of polymer blends of poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) were investigated. The bending strength and modulus of PLA/PCL tend to increase due to crystallization of the PLA phase by annealing. The mode I fracture energy, J(in), of PLA/PCL decreases dramatically due to the suppression of the ductile deformation of the spheric...

We demonstrate spatial control over cell attachment on biodegradable surfaces by flowing cell adhesive poly (D-lysine) (PDL) in a trifluoroethanol (TFE)-water mixture through microfluidic channels placed on a biodegradable poly (lactic acid)-poly (ethylene glycol) (PLA-PEG) substrate. The partial solvent mixture swells the PLA-PEG within the confines of the microfluidic channels allowing PDL to...

Compared with pristine polymers, bionanocomposites derived from biopolymers and inorganic nanoparticles have significantly improved electrical/magnetic properties, mechanical properties, thermal stability, gas barrier properties, and fire retardance. In this study, poly(lactic acid) (PLA) nanocomposites were prepared by in situ melt polycondensation of L-lactic acid with different loading ratio...

The sorption of carbon dioxide in poly(lactic acid) (PLA) was studied by quartz crystal microbalance at high pressures. To address the effect of the D isomer present in the polymer on the gas sorption, measurements were performed in PLA with two different L:D contents, 80:20 and 98:2. New data for the solubility of carbon dioxide in PLA 80:20 and PLA 98:2 over a temperature range from 303.2 to ...

Thermal degradation of poly(lactic acid) (PLA), a biodegradable and bioabsorbable polyester, has been investigated under inert atmosphere using both isothermal and dynamic heating regimes.. Two kinetic models, one for isothermal and the other for dynamic heating regims were used to fit the experimental data. It has been demonstrated that the thermal degradation of PLA is a one-stage process wit...

Poly(lactic-co-glycolic acid) (PLGA) and/or poly(lactic-acid) (PLA) microspheres are important drug delivery systems. This study investigated eye biocompatibility and safety of PLGA/PLA microspheres through intravitreal injection in rabbits. Normal New Zealand rabbits were randomly selected and received intravitreal administration of different doses (low, medium, or high) of PLGA/PLA microspher...

a poly(lactic acid) (pla) based nanocomposite active packaging has been developed for the controlled release of tert-butylhydroquinone (tbhq) antioxidant. pla based active films were loaded with tbhq (3%wt) or mixture of modified cellulose nanofiber (mcnf) (8%wt) and tbhq (3%wt) to obtain active and nanocomposite active films, respectively. release studies indicated that the release rate of tbh...

Abstract This work aims at producing and investigating, for the first time, microstructural thermo-mechanical properties of fibers constituted by poly(lactic acid) (PLA)/poly(alkylene furanoate)s (PAFs) blends textile applications. Two different PAFs have been investigated, i.e., poly(octylene furanoate) (P8F) poly(dodecylene (P12F), which blended with PLA in concentrations spun through a lab-m...

Biodegradable poly(DL-lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA) microparticles with tunable size, shape, internal structure and surface morphology were produced by counter-current flow focusing in axisymmetric (3D) glass capillary devices. The dispersed phase was composed of 0.5-2 wt % polymer solution in a volatile organic solvent (ethyl acetate or dichloromethane) and the co...