A review is given of the development of the concept of an artificial tympanic membrane. Starting with homologous tympanic membranes we compared biodegradable collagen materials (homologous and heterologous) and biodegradable synthetic materials, poly-glycolic acid, poly-lactic acid and poly-alpha-amino acids. As a non-degradable material microporous PTFE and bisphenol-A poly (carbonate) were in...

attempts have been made to prepare nanoparticles based on poly(lactic-co-glycolic acid) (plga) and doxorubicin. biological evaluation and physio-chemical characterizations were performed to elucidate the effects of initial drug loading and polymer composition on nanoparticle properties and its antitumor activity. plga nanoparticles were formulated by sonication method. lactide/glycolide ratio a...

Abstract Poly(lactic acid)/poly(butylene adipate- co -terephthalate) with a content ratio of 90/10, and its calcium carbonate (CaCO 3 ) composites nano- micro-sized particles were prepared by melt mixing. The dependence thermal mechanical properties the on particle size addition CaCO filler was investigated. composite containing five parts (abbreviated as 90 L 10 B 5m C, similarly hereinafter) ...

Lactic acid is one of the functional and valuable compounds utilized in food, pharmaceutical, and chemical industries while Poly lactic acid (PLA) is a biodegradable polymer that has a variety of applications. In recent years, microbial conversion of renewable raw materials has become an important objective in industrial biotechnology. Among many raw materials available, tapioca starch is consi...

Nanoparticle formulation is a recently developed drug delivery technology with enhanced targeting potential. Nanoparticles encapsulate the of choice and delivers it to target via molecules (ex. antigen) located on nanoparticle surface. can even be targeted deeply penetrating tissue modeled deliver drugs through blood brain barrier. These advancements are providing better disease such as cancer ...