Streptococcus pneumoniae is one of the most common etiologic agents of community-acquired pneumonia, particularly bacteremic pneumonia. Pneumolysin, a multifunctional cytotoxin, is a putative virulence factor for S. pneumoniae; however, a direct role for pneumolysin in the early pathogenesis of pneumococcal pneumonia has not been confirmed in vivo. We compared the growth of a pneumolysin-defici...

in design and optimization process of laminated composite structures, the number of layers, layer angles, stacking sequence, material types and etc should be specified. each of aforesaid parameters can be applied as a design variable. in this paper the target is to minimize the weight of laminated composite pin loaded structures. the laminated composite structures are designed based on the load...

Trucking fleets and owners of commercial vehicles utilize both new and retread tires on their vehicles in the United States. Retread tires are used primarily for the cost advantage they provide over a similar new tire. Despite the advantages that retreaded tires may bring, public perception is that retread tires are less safe than new tires as evidenced by the amount of tire debris frequently f...

Streptococcus pneumoniae is the causative agent of multiple diseases, including otitis media, pneumonia, bacteremia, and meningitis. Pneumolysin (Ply), a member of the cholesterol-dependent cytolytic pore-forming toxins, is produced by virtually all clinical isolates of S. pneumoniae, and strains in which the Ply gene has been deleted are severely attenuated in mouse models of infection. In con...

Pneumolysin (PLY), an important virulence factor of Streptococcus pneumoniae, is known to exert various effects on the host immune cells, including cytokine induction, in addition to its known cytolytic activity as a member of the thiol-activated cytolysins. It is of interest to determine whether cytolytic activity is involved in triggering the cytokine production. In this study, we constructed...

Postactivation potentiation is referred to as an acute and temporary enhancement of muscle performance resulting from previous muscle contraction. The purpose of this study was to compare the acute effect of plyometric exercise (PLY) and heavy-resistance exercise (RES) on the blood lactate level (BLa) and physical performance. Fourteen male collegiate soccer players were randomized to perform e...

The ply number of a drawing is a new criterion of interest for graph drawing. Informally, the ply number of a straight-line drawing of a graph is defined as the maximum number of overlapping disks, where each disk is associated with a vertex and has a radius that is half the length of the longest edge incident to that vertex. This paper reports the results of an extensive experimental study tha...

This study presents the results of research related to agriculture tire deformation under variable vertical load and inflation pressure. The objects were two tires same size different internal structures. Three levels pressure five used. loaded with each was scanned using 3D scanner—the effect this operation a three-dimensional image part (near place contact surface). next step creation horizon...

Streptococcus pneumoniae is the world's leading cause of pneumonia, bacteremia, meningitis and otitis media. A major pneumococcal virulence factor is the cholesterol-dependent cytolysin, which has the defining property of forming pores in cholesterol-containing membranes. In recent times a clinically significant and internationally successful serotype 1 ST306 clone has been found to express a n...

In this research study, one of the most crucial automotive engineering problems is intended to be solved. The necessity of tire pressure monitoring system is beyond doubt. Such systems are now provided relying on expensive sensors. In this study an indirect tire pressure monitoring system is proposed, utilizing identification techniques, which will reduce the cost of monitoring considerably in ...