نتایج جستجو برای: picolinamide
تعداد نتایج: 106 فیلتر نتایج به سال:
Palladium-catalyzed aminoalkynylation of electronically unbiased olefins with iodoalkynes is reported. The picolinamide auxiliary enables for the first time syn-selective mono-, di- and trisubstituted alkenes to afford corresponding pyrrolidines in up 97 % yield as single diastereomers. Furthermore, through a C−H activation approach, allows rapid synthesis functionalized olefins, which are suit...
Naproxen (NPX) is a nonsteroidal anti-inflammatory drug with pain- and fever-relieving properties, currently marketed in the sodium salt form to overcome solubility problems; however, alternative solutions for improving its solubility across all pH values are desirable. NPX is suitable for cocrystal formation, with hydrogen-bonding possibilities via the COOH group. The crystal structure is pres...
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