INTRODUCTION Diabetes is a costly and increasingly common chronic disease. Effective management of diabetes to achieve glycemic control improves patient quality of life. Adherence rates to drug regimens in patients with type 2 diabetes are relatively low and vary widely between populations. There are many factors that could affect patient adherence to drug therapy. The aim of the present study ...

In the present study the combined therapeutic approach of using an isolated compound from a herb and an oral hypoglycemic drug in alloxan-induced diabetic mice is investigated. Herbal drugs can have beneficial effects in terms of reducing the dosage, side effects and duration of action of synthetic drugs. The results show that combined therapy with 4hydroxyisoleucine and pioglitazone is more be...

OBJECTIVE Hypoglycemic treatments could modulate the risk for fractures in many ways. Most studies have not explored the effect on the incidence of bone fractures of individual oral hypoglycemic agents, rather all oral treatments as a whole. The aim of this case-control study, nested within a retrospective cohort, is the assessment of the risk for bone fractures associated with exposure to insu...

Aim: To evaluate the effect of Enalapril on blood glucose level in normal rats and interaction with the oral anti-diabetic drugs in Alloxan-induced diabetic rats. Method: The rats were classified into nine groups (n = 6).The Group I –II were normal and Group III –IX were diabetic. The experimental diabetes in rats was induced by intra-peritoneal injection of Alloxan monohydrate (135 mg/kg body ...

Background: Diabetes mellitus is a metabolic disorder requiring lifelong medication which further adds to comorbidity. Cost of the drug pays an important role in adherence and compliance treatment. There wide variation prices oral hypoglycemic drugs available Indian pharmaceutical market. Aims objectives study was planned evaluate cost antidiabetic various brands currently market either as sing...

Background and aims: Diabetic nephropathy (DN) is the most common cause of end-stage renal failure which could increase the risk of cardiovascular disease and morbidity and mortality in patients. The aim of this study was to investigate new modalities for treatment of diabetic nephropathy. Methods:This study was a mini-review research to investigate drugs that are used for DN treatment. Resul...

background and aims: diabetic nephropathy (dn) is the most common cause of end-stage renal failure which could increase the risk of cardiovascular disease and morbidity and mortality in patients. the aim of this study was to investigate new modalities for treatment of diabetic nephropathy. methods:this study was a mini-review research to investigate drugs that are used for dn treatment. results...

A randomized double blind placebo controlled trial was conducted to determine the efficacy of Tinospora crispa as additional treatment in patients with type 2 diabetes mellitus who did not respond to oral hypoglycemic drugs and refused insulin injection. Twenty patients were allocated to receive Tinospora crispa powder in capsule form at a dosage of 1 gram thrice daily for 6 months. Twenty pati...