نتایج جستجو برای: oculomotor muscles

تعداد نتایج: 59974  

2016
Guido Maiello William J. Harrison Peter J. Bex

Most eye movements in the real-world redirect the foveae to objects at a new depth and thus require the co-ordination of monocular saccade amplitudes and binocular vergence eye movements. Additionally to maintain the accuracy of these oculomotor control processes across the lifespan, ongoing calibration is required to compensate for errors in foveal landing positions. Such oculomotor plasticity...

Journal: :Investigative ophthalmology & visual science 2012
Jonathan T Erichsen Paul J May

PURPOSE We determined the distribution of cells containing synthetic enzymes for the unconventional neurotransmitter, nitric oxide, with respect to the known populations within the oculomotor complex. METHODS The oculomotor complex was investigated in monkeys and cats by use of histochemistry to demonstrate nicotinamide adenine dinucleotide phosphate diaphorase positive (NADPHd(+)) cells and ...

Journal: :Journal of neurology, neurosurgery, and psychiatry 2000
C Tilikete C Vial M Niederlaender P L Bonnier A Vighetto

Ocular neuromyotonia in the muscles innervated by the right oculomotor nerve was diagnosed in a patient without a history of radiation therapy. Electromyography of the levator palpebrae showed continuous motor unit activity. Brain MRI disclosed a close contact between the right third cranial nerve and a basilar artery dolichoectasia. The patient partly benefited from carbamazepine therapy. This...

Journal: :Vision research 1987
M J Steinbach

The peripheral and central apparatus for extraretinal (non-visual) sensing of eye position by proprioception (inflow) is documented. The functional significance of this inflowing signal is shown by its role in (1) providing oculomotor stability in fixation and conjugacy, (2) specification of visual direction, (3) development of some visual functions, and (4) depth and vergence responses. Inflow...

Journal: :The Journal of experimental biology 1980
D Mellon G Lnenicka

The morphologies and passive electrical parameters of fibres in two eye muscles of a surface- and a cave-dwelling crayfish were compared. In the cave-dwelling form the muscles contained fewer fibres, of less diameter, and hence had a smaller cross-sectional area. Current-voltage relationships were similar in both species. Input resistance was higher in the cave-dweller, but the difference was n...

Journal: :American journal of human genetics 2016
Jong G Park Max A Tischfield Alicia A Nugent Long Cheng Silvio Alessandro Di Gioia Wai-Man Chan Gail Maconachie Thomas M Bosley C Gail Summers David G Hunter Caroline D Robson Irene Gottlob Elizabeth C Engle

Duane retraction syndrome (DRS) is a congenital eye-movement disorder defined by limited outward gaze and retraction of the eye on attempted inward gaze. Here, we report on three heterozygous loss-of-function MAFB mutations causing DRS and a dominant-negative MAFB mutation causing DRS and deafness. Using genotype-phenotype correlations in humans and Mafb-knockout mice, we propose a threshold mo...

Journal: :Neuron 2014
Long Cheng Jigar Desai Carlos J. Miranda Jeremy S. Duncan Weihong Qiu Alicia A. Nugent Adrianne L. Kolpak Carrie C. Wu Eugene Drokhlyansky Michelle M. Delisle Wai-Man Chan Yan Wei Friedrich Propst Samara L. Reck-Peterson Bernd Fritzsch Elizabeth C. Engle

The ocular motility disorder "Congenital fibrosis of the extraocular muscles type 1" (CFEOM1) results from heterozygous mutations altering the motor and third coiled-coil stalk of the anterograde kinesin, KIF21A. We demonstrate that Kif21a knockin mice harboring the most common human mutation develop CFEOM. The developing axons of the oculomotor nerve's superior division stall in the proximal n...

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