نتایج جستجو برای: ntd
تعداد نتایج: 1309 فیلتر نتایج به سال:
1 Centre for Global Health, Institute for Infection and Immunity, St George’s, University of London, London, United Kingdom, 2 Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America, 3 Medecins Sans Frontières Access Campaign, Médecins Sans Frontières, Geneva, Switzerland, 4 National Institute for Communicable Diseases (Centre for Healthc...
The present work analyses climatological variations of Convective Available Potential Energy (CAPE) and Inhibition (CIN) over the eastern India (Odisha, West Bengal Jharkhand) during pre-monsoon season, where thunderstorms are frequent disastrous. utilises European Centre for Medium-Range Weather Forecast (ECMWF) reanalysis data: ERA-5 1987-2016, supplemented with information about thunderstorm...
Umami taste perception is mediated by the heterodimeric G-protein coupled receptors (GPCRs), formed by the assembly of T1R1 and T1R3 subunits. T1R1 and T1R3 subunits are class C GPCRs whose members share common structural homologies including a long N-terminal domain (NTD) linked to a seven transmembrane domain by a short cysteine-rich region. The NTD of the T1R1 subunit contains the primary bi...
Objective: Neural tube defect (NTD) incidence could be effectively reduced by folic acid supplementation before and during pregnancy. We studied single nucleotide polymorphisms (SNPs) involved in folate metabolism to explore genetic susceptibility to NTD. We studied the association between 12 SNPs involved in 11 folate metabolism genes and NTDs. Methods: We enrolled 76 children with NTD and 188...
Background: CaBP7 is an EF-hand-containing transmembrane protein that inhibits PI4KIII activity. Results: PI4KIII interacts with CaBP7 NTD, which exhibits an expansive hydrophobic pocket. Conclusion: The structure of CaBP7 NTD is similar to that of CaM NTD but has a more expansive hydrophobic pocket containing fewer methionine residues. Significance: Regulation of PI4P synthesis is essential fo...
Steroid receptors are conditional transcription factors that, upon binding to their response elements, regulate the expression of target genes via direct protein interactions with transcriptional coactivators. We have analyzed the functional interactions between the androgen receptor (AR) and 160-kDa nuclear receptor coactivators. Upon overexpression in mammalian cells, these coactivators enhan...
Neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose; NTD) is an amino-sugar antibiotic produced by several Bacillus species that functions as an autoinducer by activating its own biosynthetic operon, ntdABC. We previously reported that the introduction of a certain rpoB mutation (rpoB5) into Bacillus subtilis enables the cells to overproduce NTD. B. subtilis mini-Tn10 transposan...
OBJECTIVE To investigate the contribution of polymorphic variation in genes involved in the folate-dependent homocysteine pathway in the aetiology of neural tube defects (NTD). DESIGN Case-control association study. SUBJECTS A total of 530 individuals from families affected by NTD, 645 maternal controls, and 602 healthy newborn controls from the northern UK. MAIN OUTCOME MEASURES Seven po...
OBJECTIVE To predict neural tube birth defect (NTD) using support vector machine (SVM). METHOD The dataset in the pilot area was divided into non overlaid training set and testing set. SVM was trained using the training set and the trained SVM was then used to predict the classification of NTD. RESULT NTD rate was predicted at village level in the pilot area. The accuracy of the prediction ...
A total of 227 mothers enrolled for periconceptional multivitamin supplementation because of previous neural tube defect (NTD) births took vitamins for less than the recommended minimum period (at least 28 days before conception until two menstrual periods have been missed). Of 213 examined infants/fetuses born to these partially supplemented mothers, two had NTD, one of whom followed four prev...
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