background: sulfur mustard (sm) has acute and chronic effects on skin and mucosal surfaces. the aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to sm in iran-iraq war nearly 25 years ago.   methods : one hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastro-duodenoscopy. of them, 52 cases had been exp...

background: reflux disease is a common gastrointestinal problem. the association between reflux disease and gastritis pattern is controversial. aim : to determine the association between reflux disease and gastritis pattern in patients with helicobacter pylori (h. pylori) infection. methods: 470 patients with dyspepsia and reflux disease were enrolled in this study. the inclusion criteria were ...

BACKGROUND Gastroesophageal reflux disease is a worldwide prevalent condition that exhibits a large variety of signs and symptoms of esophageal or extra-esophageal nature and can be related to the esophagic adenocarcinoma. In the last few years, greater importance has been given to the influence of physical exercises on it. Some recent investigations, though showing conflicting results, point t...

There is a growing evidence that gastroesophageal reflux disease is related to several upper gastrointestinal cancers, mainly the esophageal adenocarcinoma and a certain type of gastric cardia adenocarcinoma. Currently, the incidence of gastroesophageal reflux disease is rapidly increasing in Korea. Therefore, there is a possibility of such increasing cancerous incidents, similar to the western...

Objective: To assess the knowledge and practice of pediatricians about infants with physiological reflux and gastroesophageal reflux disease. Methods: 140 pediatricians were interviewed during two scientific events in 2009 and 2010. The questions referred to two clinical cases of infants. One with symptoms of infant regurgitation (physiological reflux) and another with gastroesophageal reflux d...

BACKGROUND Portal hypertension in patients with liver cirrhosis causes manifestations such as esophageal varices, ascites and edema. Some studies have been conducted about the role of esophageal varices in the development of esophageal motor disorders and abnormal gastroesophageal reflux in these patients. Ascites could be a factor promoting gastroesophageal reflux and it has been questioned wh...

A 15-year-old girl was referred with a 2-year history of perennial non-productive cough, which had been preceded by Mycoplasma pneumoniae pneumonia and subsequent asthma. Symptoms were only partially responsive to anti-asthma treatment including an inhaled corticosteroid and a leukotriene receptor antagonist. The patient's BMI was 27.8; she had gained over 10 kg in the previous two years. Typic...

Gastroesophageal reflux is a very common disease. Almost everybody experiences heartburn from time to time but with different degree of severity. How does reflux occur, and which factors encourage or work against reflux is a very controversial matter. This article covers all controversial issues about the pathophysiology of gastroesophageal reflux and discusses the old and recent understanding ...

Gastroesophageal reflux disease (GERD) is a common condition that presents with symptoms of heartburn and regurgitation. Asthma is an equally common medical condition that often coexists with GERD. The clinical scenario of difficult-to-treat asthma in the setting of concomitant GERD leads to the possibility of GERD-induced asthma. However, asthma may also induce GERD, so confusion has developed...