introduction: since organophosphorus compounds (op) are toxic and designed to destroy insects and pest species, there are many hazards associated with their use. although, the main target site of these compounds is acetylcholinesterase (ache), however it has become increasingly evident that ops have also other direct effects on cellular processes. in the present study, the effects of low concen...

To evaluate the effects of hyperglycemia and insulin treatment on proportion serotonin-immunoreactive (5-HT-IR) myenteric neurons, samples were taken from duodenum, ileum, colon diabetic, insulin-treated control rats 10 weeks after onset streptozotocin-induced hyperglycemia. Myenteric whole-mount preparations immunostained with anti-5-HT pan-neuronal anti-HuCD markers. In controls, 5-HT-IR neur...

This study aimed to assess the relationship between age-related changes in Neurofilament Light Chain (NFL), a marker of neuronal function, and various factors including muscle body composition, metabolomic markers. The included 40 participants, aged 20 85 years. NFL levels were measured, markers assessed. increased significantly with age, particularly men. Negative correlations found measures s...

generation neural stem cells from neurosphere–derived bone marrow stem cells using bioactive substance atc. bone marrow cells (bmscs) were isolated from rat. bmscs cultured by dmem/f12 medium supplemented with 10% fetal bovine serum. these cells evaluated by specific markers of bmscs such as bioactive substance atc, b27. then bmscs differentionated in to neurosphere and divided in two groups wh...

Recent studies of the olfactory system report that differentiated sensory neurons have an identity evidenced by surface markers. These markers relate to the specificity of the neuron's odorant receptor. During axonal outgrowth the markers co-determine, with which of the second stage neurons synapses are formed. The markers and the resulting connectivity (or network structure) amount to static, ...

PURPOSE The purpose of this study was to investigate the presence of progenitor cells in the uninjured, adult rat lacrimal gland (LG). METHODS The presence of progenitor cells was examined in LG sections from male rats using antibodies against selected stem cell markers and α-smooth muscle actin (SMA), which marks myoepithelial cells (MECs), by immunofluorescence microscopy (IF). Small, immat...

Endometrial stromal cells (EMSCs) obtained from porcine uterus (n = 6) were positive for mesenchymal stem cell markers (CD29, CD44 and CD90), and negative for epithelial marker CD9 and hematopoietic markers CD34, CD45 analyzed by flow cytometry. Further the cells were positive for expression of mesenchymal markers, CD105, CD140b, and CD144 by PCR. Pluripotent markers OCT4, SOX2, and NANOG were ...

The dental follicle is an ectomesenchymal tissue surrounding the developing tooth germ. Human dental follicle cells (hDFCs) have the capacity to commit to differentiation into multiple cell types. Here we investigated the capacity of hDFCs to differentiate into neural cells and the efficiency of a two-step strategy involving floating neurosphere-like bodies for neural differentiation. Undiffere...

BACKGROUND NIK- and IKK2-binding protein (NIBP)/TRAPPC9 is expressed in brain neurons, and human NIBP mutations are associated with neurodevelopmental disorders. The cellular distribution and function of NIBP in the enteric nervous system (ENS) remain unknown. METHODS Western blot and reverse transcription-polymerase chain reaction analysis were used respectively to identify the protein and m...

context the current study aimed to review research articles concerning cortical representational plasticity following the manipulations of inputs. evidence acquisition this review article compromised previous studies in pubmed, google scholar and scientific information databases according to the keywords since 1988. results ca1 neurons depolarization paired with ca3 presynaptic input result in ...