background peripheral nerve repair is often complicated by fibroblastic scar formation, nerve dysfunction, and traumatic neuroma formation. use of silicone may improve outcomes of these repairs. in this study, we tried to evaluate effectiveness of silicone gel on rats’ sciatic nerve repair, axon regeneration and scar formation around and in the nervous tissues. methods this experimental study w...

peripheral nerve injuries caused by traffic accidents, resections of tumors or iatrogenic side effects of the surgeries are few of the most common form of trauma occurring with up to 500,000 cases each year in iran. conventional strategies including nerve coaptation, and the application of autografts, allografts and xenografts are restricted due to the limited availability of donors, immune-rej...

spinal cord injury (sci) results in the damage of motor and sensory pathways. the molecular and cellular structure of the injury milieu has been shown to be vital for endogenous regeneration in most tissues. regeneration of injured central nervous system (cns) is limited by damaged cell environment. biomaterial scaffolds can reconstruct injured cns tissue following sci by promoting the migratio...

Experimental and clinical studies have reported that testosterone has a critical role in the maintenance of homeostatic and morphologic corpus cavernosum components, essential for normal erectile physiology. Although the exact mechanisms mediated by testosterone in erectile function are still under investigation, recent research has suggested an important role in the regulation of endothelial c...

one of the important reasons for death among the worldwide’s population is trauma which is injury or damage to a biological organism caused by physical harm from an external source. after trauma, the immune system and the early inflammatory immune response activation lead to massive injury. trauma causes activation of nearly all components of the immune system; it also activates the neuroendocr...

tuberculous spondylitis is not an uncommon disease of the spine. near one percent of all cases of spinal tuberculosis (tb) involves craniocervical junction. hypoglossal nerve palsy is not an uncommon neurological finding, but isolated involvement of the hypoglossal nerve is rare and limited to case reports or small case series. here, we report a case of craniocervical junction tuberculosis pres...