A middle-aged male presenting with marked eosinophilia and multisystem disease http://ow.ly/Z7JX301ABjF.

Brain stem potentials from three groups of patients, namely those with pure progressive autonomic failure, Parkinson's disease and multisystem atrophy with progressive autonomic failure (Shy-Drager syndrome) were compared with each other and a group of normal subjects. In virtually all the patients with multisystem atrophy with progressive autonomic failure the brain stem potentials were abnorm...

Histiocytosis is a heterogenous group of disorders that are characterized by proliferation and activation of mononuclear phagocyte system. Langerhans Cell Histiocytosis (LCH) or Class I histiocytosis is a rare disorder of unknown etiology with proliferation of Langerhan cells which may infiltrate a single or multiple organs. This disease is more common in infants and children. It is usually spo...

Behcet’s disease is a multisystem disease characterized clinically by oral aphthae and occasionally by genital aphthae, cutaneous lesions such as pustular vasculitis, sweet syndrome-like, pyoderma gangrenosum-like and erythema nodosum-like lesions and variably present systemic features such as synovitis, anterior and posterior uveitis, meningoencephalitis and large vessel smaller vessel vascula...

OBJECTIVES To describe the morphologic characteristics of skin lesions, extent of extracutaneous disease, and outcomes in patients with neonatal presentation of Langerhans cell histiocytosis (LCH), and to examine clinical predictors of disease prognosis. DESIGN Retrospective validation cohort study. Maximum duration of follow-up was 10 years. SETTING A tertiary care children's hospital in C...