The redetermined structure of 9α,21-dichloro-11β,17α-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-17-yl furan-2-carboxylate monohydrate, C27H32Cl2O7·H2O, at 100 K has triclinic (P1) symmetry. The structure displays O-H...O hydrogen bonding, which gives rise to infinite sheets extending parallel to the [110] plane. The previously published structure [Chen et al. (2005). J. Pharm. Sci. 94, 2496...

Long-term use of topical nasal steroids (especially older generation steroids) has been shown to elevate intraocular pressure (IOP), but newer intranasal steroids are thought to have a minimal effect on IOP because of their low bioavailability. This study aimed to investigate alterations in IOP with two commonly used intranasal steroids for a 6-month period of time. One-hundred allergic rhiniti...

The case of a 22 month old male infant is reported, who underwent BCG vaccination five days after his birth. Almost 4 months after the vaccination, an abscess developed at the site of the injection. Mildly itching, circular to oval macular lesions appeared first surrounding the abscess, then spread over the entire body. The rash was successfully treated with topical emollients and mometasone fu...

We report a case study of a 55-year-old white male with severe persistent refractory corticosteroid-dependent asthma receiving inhaled combination therapy with fluticasone propionate 500 mug and salmeterol 50 mug twice-daily in addition to 6-week cycles of oral corticosteroid treatment for the previous 7 months. The patient was switched to high-dose mometasone furoate delivered via a dry powder...

Correction for 'Magnetic relaxation versus 3D long-range ordering in {Dy2Ba(α-fur)8}n furoate polymers' by E. Bartolomé et al., Dalton Trans., 2014, 43, 10999-11013.

This study evaluated the effect of mometasone furoate (MF)/formoterol (F) versus its monocomponents, each administered via metered-dose inhaler, on asthma deteriorations and lung function. This 26-week, multicentre, double-blind, placebo-controlled study included subjects aged ≥12 yrs with not well-controlled asthma on low-dose inhaled corticosteroids. After a 2-3-week open-label run-in (MF 100...

Background The availability of controller therapies at multiple strengths is important to treat different severities of asthma (NHLBI and GINA guidelines). The clinical effect of medium-dose mometasone furoate/formoterol (MF/F) combination administered via single inhaler had never been characterized in asthmatic subjects versus placebo. We investigated the effect of medium-dose MF/F administere...

OBJECTIVE To analyze the efficacy of treating postviral olfactory loss with glucocorticoids, Ginkgo biloba, and mometasone furoate nasal spray. DESIGN Randomized trial. SETTING Academic research. PATIENTS Seventy-one patients who were diagnosed as having postviral olfactory loss. MAIN OUTCOME MEASURES All patients underwent olfactory function tests, including the butanol threshold test ...

The commercially available inhaled corticosteroids (ICS) for asthma treatment are beclomethasone dipropionate (BDP), budesonide (BUD), ̄unisolide (FLU), ̄uticasone propionate (FP), mometasone furoate (MF), and triamcinolone acetonide (TA); most of them are also available as nasal sprays for the treatment of rhinitis. There is no longer any doubt of their effectiveness in both asthma and rhinitis....