Considering the load-bearing physiological requirement of articular cartilage, scaffold for cartilage tissue engineering should exhibit appropriate mechanical responses as natural cartilage undergoing temporary deformation on loading with little structural collapse, and recovering to the original geometry on unloading. A porous elastomeric poly l-lactide-co-ɛ-caprolactone (PLCL) was generated a...

Drug delivery carriers can maintain effective therapeutic concentrations in the eye. To this end, we developed lipid nanoparticles (L/NPs) in which the surface was modified with positively charged chitosan, which engaged in hydrogen bonding with the phospholipid membrane. We evaluated in vitro corneal permeability and release characteristics, ocular irritation, and drug dynamics of modified and...

We present an ink platform for a printable polymer-graphene nanocomposite that is intended for the development of modular biosensors. The ink consists of catechol-modified chitosan and reduced graphene oxide decorated with platinum nanoparticles (rGO-Pt). We modified the chitosan with catechol groups, in order to obtain adhesive properties and improve solubility. Dispersions of rGO-Pt in ethyle...

In the present investigation chitosan has been chemically modified by treating with two different aldehydes like acetaldehyde and propionaldehyde to form Schiff's bases. Schiff's bases of chitosan with acetaldehyde and propionaldehyde were named as polymer A and polymer B, respectively. Fourier Transform Infra Red (FTIR) spectral data have confirmed the reaction carried out on chitosan. Drug fr...

background: extensive full-thickness burns require replacement of both epidermis and dermis. in designing skin replacements, the goal has been to re-create this model and make a product which has both essential components. methods: in the present study, we developed procedures for establishing confluent, stratified layers of cultured human keratinocytes on the surface of modified collagen-chito...

Chitosan was modified by coupling with linoleic acid through the 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide-mediated reaction to increase its amphipathicity for improved emulsification. The micelle formation of linoleic acid-modified chitosan in the 0.1 M acetic acid solution was enhanced by O/W emulsification with methylene chloride, an oil phase. The fluorescence spectra indicate that with...

In this work, a simple and sensitive electrochemical method was developed to determine Sudan I by cyclic voltammetry and differential pulse voltammetry using a glassy carbon electrode modified with a chitosan/carbon nanotube composite. In cyclic voltammetry, Sudan I exhibited a well-defined oxidation peak located at 0.72 V at the multi-walled carbon nanotube (MWCNT)/chitosan-modified GCE. The d...

Chitosan, a copolymer of glucosamine and N-acetyl glucosamine, is a polycationic, biocompatible and biodegradable polymer. In addition, chitosan has different functional groups that can be modified with a wide array of ligands. Because of its unique physicochemical properties, chitosan has great potential in a range of biomedical applications, including tissue engineering, non-viral gene delive...

In any repair of a tooth with permanent restorative materials, the interface is always a sensitive region. The appearance of adhesive materials was a great step forward in dealing with the problems of this region and improving the overall performance of the restorations. However, contemporary adhesive materials do have a major disadvantage, namely that their durability is limited, a limitation ...

Several techniques have been used for sand production control in sandstone reservoirs.The main objective of this research is to present a suitable resin to be used as a consolidation agent in oil reservoirs. To achieve this purpose, urea-formaldehyde resin, phenol-formaldehyde resin, and modified urea-formaldehyde resin were selected to be studied. Core samples were made by the sand sample prov...